26 expresses the activity as a function of the aminopyridine pK , the interaction energy with the receptor, and a quotient a 27 of partition functions. Molecular quantum similarity theory is introduced in the model to express the activity as a 28 function of the principal components of the similarity matrix for a series of agonists. To validate the model, a set of 29 five active (protonated) am...

In the present work, complexes of cobalt(II), copper(II), and zinc(II), 2-amino-4-methylpyrimidineand, 2,3-diaminopyridine were successfully prepared characterized using elemental analysis, UV-visible, FTIR spectroscopy, as well magnetic susceptibility measurements, molar conductance, TGA X-ray diffraction. From spectral data, formulae [M(L1)(L2)Cl2(H2O)] (where L1 = AMPY (2-amino-4-methylpyrim...

A novel photoresponsive functional monomer bearing diaminopyridine and azobenzene moieties was synthesized and applied to the preparation of photo-regulated molecularly imprinted polymers, which can recognize porphyrin derivatives through hydrogen bonding. The binding affinity of the imprinted cavities was regulated by UV irradiation, suggesting that azobenzene groups located inside the binding...

A new metal-free macrocyclic Schiff base ligand bearing two metal cavities incorporated with sets of N3O2 donor atoms derived from 2, 6-diaminopyridine and isatine was synthesized. The used to prepare homo hetero binuclear complexes Ni (II), Cu ZrO (II) Ba ions. were characterized using Fourier transform infrared (FT-IR), UV–vis, mass spectroscopy, elemental analysis (CHN), thermo gravimetric (...