A laser photolysis–long path laser absorption (LP-LPLA) experiment has been used to determine the rate constants for H-atom abstraction reactions of the dichloride radical anion (Cl2) in aqueous solution. From direct measurements of the decay of Cl2 in the presence of different reactants at pH 5 4 and I 5 0.1 M the following rate constants at T 5 298 K were derived: methanol, (5.1 6 0.3) · 104 ...

Lymphohematopoiesis, cell matrix adhesion, homing of leukocytes, T cell activation, and tumor metastasis are mediated through the CD44 family of cell surface receptors. We have recently shown that anti-CD44 mAb trigger protein tyrosine kinase-dependent activation of T cell effector functions. Here, we show that hyaluronate (HA), a CD44 ligand, in conjunction with CD3/TCR-mediated stimuli, is co...

BACKGROUND AND OBJECTIVES Minor histocompatibility antigen (mHag)-specific graft-versus-leukemia reactivities are observed following unselected donor lymphocyte infusion for the treatment of relapse after HLA-matched mHag-mismatched stem cell transplantation (SCT). Adoptive transfer of donor-derived ex vivo-generated HA-1-specific oligoclonal T cells or HA-1 peptide patient vaccination are curr...

Serum hyaluronic acid (HA) is a well-established marker of fibrosis in patients with chronic liver disease (CLD). However, the relationship between serum HA level and protein-energy malnutrition (PEM) in patients with CLD is an unknown. We aimed to examine the relationship between serum HA level and PEM in patients with chronic hepatitis C (CHC) compared with the relationships of other serum ma...

Recent studies have suggested that statins, the inhibitors for 3-hydroxy-3-methyglutaryl (HMG)-CoA reductase in the mevalonate pathway, exhibit anti-inflammatory effects. However, the immune modulatory effects of statins on the differentiation of CD4(+) T cells and their underlying mechanisms are still largely unknown. To address these issues, we examined the effect of simvastatin and inhibitor...

1997. The relation among gonadal steroids, immunocompetence, body mass, and behavior in young Black-headed Gulls (Larus ridibundus). American Naturalist 150:201–219. SAINO, N., A. P. MøLLER, AND A. M. BOLZERN. 1995. Testosterone effects on the immune system and parasite infestations in the Barn Swallow (Hirundo rustica): An experimental test of the immunocompetence hypothesis. Behavioral Ecolog...

A trial was conducted in a 7-year old citrus orchard of the National Horticultural Research Institute, Nigeria, to investigate the effect of different levels of organo-mineral fertilizers as it affect the economic returns of sweet orange (Citrus sinensis L. Osbeck var. Agege 1). The treatments consisted of: (1). 10 tha Poultry 1 manure (PM), (2). 15 t ha PM, (3) 20 t ha-1 PM, (4). 0.45 t ha NPK...

BACKGROUND Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens (MHC-I) and costimulatory molecules. We have previously shown that geranylgeranyl transferase inhibition (done with GGTI-298) stimulates anti-melanoma immune response through MHC-I and costimulatory molecule expression in the B16F10 murine mod...

We report here identification of novel mimicry epitopes for interphotoreceptor retinoid-binding protein (IRBP) 201–216, a candidate ocular antigen that causes experimental autoimmune uveoretinitis (EAU) in A/J mice. One mimicry epitope from Ehrlichia canis (EHC), designated EHC 44–59, induced cross-reactive T cells for IRBP 201–216 capable of producing T helper (Th)1 and Th17 cytokines, but fai...

In this note we are concerned with interior regularity properties of the $p$-Poisson problem $\Delta_p(u)=f$ $p>2$. For all $0<\lambda\leq 1$ constuct right-hand sides $f$ differentiability $-1+\lambda$ such that (Besov-) smoothness corresponding solutions $u$ is essentially limited to $1+\lambda / (p-1)$. The statements local nature and cover integrability parameters. They particularly imply o...