1-(Benzyloxycarbonylamino)-hex-5-en-3-ol undergoes a novel Pd(II)/CuCl2-catalysed bicyclisation to furnish the corresponding 6-oxa-2-azabicyclo[3.2.1]octane in good yield.

A new highly efficient three-component reaction of alkyl acrylate, aldehyde and dialkyl malonate using ethyl diphenylphosphine as organocatalyst has been described. Various highly functional compounds bearing hydroxyl groups and the ester functions can be easily prepared in moderate to good yields according to our one-step procedure. The reactions are believed to proceed via Morita-Baylis-Hillm...

[reaction: see text] A novel palladium-catalyzed coupling reaction between two Csp(3)-Csp(3) centers has been investigated. This protocol is initiated by the oxidative addition of an alpha-halo carbonyl compound to a palladium(0) species, followed by the double transmetalation. The key dialkyl palladium intermediate undergoes reductive elimination to form the desired coupling product.

We report here that polysubstituted dihydroisoquinolones and isoquinolones can be constructed by the one-pot reaction of the readily available acyclic α,β-unsaturated carbonyl precursors and dialkyl glutaconates under mild basic conditions (1-45 min for the former vs. 1-6 h for the latter) via the domino process involving [3+3] annulation/intramolecular aza-cyclization.

The title complex, dicarbonyl-3κ(2)C-(μ(3)-3,6-dimethyl-3,6-diaza-octane-1,8-dithiol-ato-1:2:3κ(7)S:S,N,N',S':S,S')(μ(2)-3,6-di-methyl-3,6-diaza-octane-1,8-dithiol-ato-1:2κ(5)S,N,N',S':S)-1,2-diiron(II)-3-nickel(0) [Fe(2)Ni(C(8)H(18)N(2)S(2))(2)(CO)(2)], is the second example showing M(μ-SR)(2)Ni(0)(CO)(2) coordination (M = any metal atom). Both Fe(II) ions are five-coordinated in distorted tri...

Stable derivatives of oxaphosphaphenanthrenes were prepared using multicomponent reactions of 3-bromo-2-naphthol, dialkyl acetylenedicarboxylate and trimethyl or triphenyl phosphite under microwave conditions with good yields. 

Catalytic reforming is a chemical process utilized in petroleum refineries to convert naphtha, typically having low octane ratings, into high octane liquid products, called reformates, which are components of high octane gasoline. In this study, a mathematical model was developed for simulation of semi-regenerative catalytic reforming unit and the result of the proposed model was compared with ...

The title compound, C(26)H(38)O(3), was prepared by an intra-molecular Claisen-like cyclization of ethyl 2-acet-oxy-4,4-dimethyl-1-(3-methyl-but-2-en-yl)cyclo-hex-2-enecarboxyl-ate followed by dialkyl-ation. One of the methyl groups is disordered over two sets of sites in a 0.67:0.33 ratio.

The molecular structure of the bulky primary silane, (Me(3)Si)(3)CSiH(3), in the gas phase has been determined by electron diffraction. Photolysis of (Me(3)Si)(3)CSiH(3) affords a convenient route to the bulky dialkyl disilane, [(Me(3)Si)(3)CSiH(2)](2), which is the first 1,2-dialkyldisilane to be structurally characterised by single-crystal X-ray diffraction. The disilane has an unusually larg...

We report studies of the evaporation and discharge dynamics of highly charged droplets generated by electrospray ionization from n-heptane, n-octane, and p-xylene doped with Stadis-450, a conductivity-enhancing agent. A phase Doppler anemometer (PDA) characterizes individual droplets moving through the uniform electric field within an ion mobility cell according to size, velocity, and charge. R...