RATIONALE Ubiquitin-proteasome system (UPS) dysfunction has been implicated in cardiac pathogenesis. Understanding how cardiac UPS function is regulated will facilitate delineating the pathophysiological significance of UPS dysfunction and developing new therapeutic strategies. The COP9 (constitutive photomorphogenesis mutant 9) signalosome (CSN) may regulate the UPS, but this has not been test...

this paper presents the new topology of three phase on line uninterruptible power supply (ups) by employing t-source inverter (tsi) with maximum constant boost pulse width modulation (pwm) control and the results are compared with the conventional uninterruptible power supply (ups). the conventional ups consists of voltage source inverter (vsi) with step up transformer or dc-dc booster which de...

In the first part of the paper, we give an explicit algorithm to compute the (genus zero) Gromov-Witten invariants of blow-ups of an arbitrary convex projective variety in some points if one knows the Gromov-Witten invariants of the original variety. In the second part, we specialize to blow-ups of Pr and show that many invariants of these blow-ups can be interpreted as numbers of rational curv...

The functional approach of the Technological Innovation System (TIS) has become important in innovation theory to understand the dynamics of technological innovations. Until now, TIS has mainly been applied topdown from a policy perspective. The aim of this study was to investigate whether TIS can be used in the management domain, from an actororiented perspective, to explain the dynamics in wh...

In the first part of the paper, we give an explicit algorithm to compute the (genus zero) Gromov-Witten invariants of blow-ups of an arbitrary convex projective variety in some points if one knows the Gromov-Witten invariants of the original variety. In the second part, we specialize to blow-ups of Pr and show that many invariants of these blow-ups can be interpreted as numbers of rational curv...

In the first part of the paper, we give an explicit algorithm to compute the (genus zero) Gromov-Witten invariants of blow-ups of an arbitrary convex projective variety in some points if one knows the Gromov-Witten invariants of the original variety. In the second part, we specialize to blow-ups of Pr and show that many invariants of these blow-ups can be interpreted as numbers of rational curv...

Gender differences in the efficacy of nicotine replacement therapies (NRTs) were examined in a meta-analytical review of 90 effect sizes obtained from a sample of 21 double-blind, placebo-controlled randomized studies. Although NRT was more effective for men than placebo at 3-month, 6-month, and 12-month follow-ups, the benefits of NRT for women were clearly evident only at the 3- and 6-month f...

The purpose of this survey was to investigate the relationship between demographic characteristics and willingness of patients to pay for regular dental check-ups in Japan. Questionnaires were distributed at private dental offices and collected via postage-paid return envelopes addressed to the center of the study groups. Questions focused on demographics and willingness to pay for regular chec...