The Affibody molecule Z(HER2:342-pep2), site-specifically and homogeneously conjugated with a 1,4,7,10-tetra-azacylododecane-N,N',N'',N'''-tetraacetic acid (DOTA) chelator, was produced in a single chemical process by peptide synthesis. DOTA-Z(HER2:342-pep2) folds spontaneously and binds HER2 with 65 pmol/L affinity. Efficient radiolabeling with >95% incorporation of (111)In was achieved within...

AMA Chen W, Shi Z, Feng J, et al. Effects of severe hydronephrosis on surgical outcomes minimally invasive percutaneous nephrolithotomy (MPCNL). Videosurgery and Other Miniinvasive Techniques. 2023;18(2):328-342. doi:10.5114/wiitm.2023.128055. APA Chen, W., Shi, Z., Feng, J., Liu, C., Jiang, T., & Q. (2023). Techniques, 18(2), 328-342. https://doi.org/10.5114/wiitm.2023.128055 Chicago Wenwei, Z...

For the last several years, I have been studying astronomical nebulae, and the work has slowly led to a desire to know more about atomic structure calculations. The state of these nebulae (temperature, densities, abundances, etc) are typically constrained through the use of diagnostic emission line ratios as detailed in Osterbrock & Ferland (2006). For example, doubly ionized oxygen is characte...

, 118 (2013); 342 Science et al. Arne Weiberg Interference Pathways Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA This copy is for your personal, non-commercial use only. clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Permission ...

Tapasin has been shown to stabilize TAP and to link TAP to the MHC class I H chain. Evidence also has been presented that tapasin influences the loading of peptides onto MHC class I. To explore the relationship between the ability of tapasin to bind to TAP and the MHC class I H chain and the ability of tapasin to facilitate class I assembly, we have created novel tapasin mutants and expressed t...

*Corresponding author: Paolo Madeddu, Professor, MD CS FAHA, Chair Experimental, Cardiovascular Medicine, Head of Regenerative Medicine Section, Bristol Heart Institute, School of Clinical Sciences, University of Bristol, Level 7, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, United Kingdom, Tel: 0044 (0)117 342 3904, 0044 077 691 55 205(mobile) ; Fax: 0044 (0)117 342 3904; E-...

MicroRNAs (miRNAs) have emerged as one of the crucial regulators of cancer progression. Some miRNAs are reported to be related to the response of breast cancer to tamoxifen (TAM). In this study, we investigated whether the levels of TAM response-related miRNAs translate to patient survival. The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets were used and Gene Set Enrichme...

The detection of 22GHz water vapor emission from IC 342 is reported, raising the detection rate among northern galaxies with IRAS point source fluxes S100μm > 50 Jy to 16%. The maser, associated with a star forming region ∼10–15 west of the nucleus, consists of a single 0.5 kms wide feature and reaches an isotropic luminosity of 10 L⊙ (D=1.8Mpc). If the time variability is intrinsic, the maser ...