BACKGROUND Emerging evidence indicates an association between cognitive function and physical performance in late life. This study examines the relationship between cognitive function and subsequent gait speed decline among high-functioning older adults. METHODS Measures of global cognitive function (Modified Mini Mental State Examination [3MS]) and executive control function (ECF) (a clock d...

OBJECTIVE It has been hypothesized that individuals without dementia with Alzheimer disease (AD) neuropathology may be in the preclinical stages of dementia and could be experiencing subtle cognitive decline. The purpose of this study was to compare longitudinal cognitive performance in oldest-old individuals without dementia with and without AD neuropathology. METHODS The study included 58 i...

In a recent paper a model of quark and lepton masses was proposed. Without any family symmetries almost all the qualitative and quantitative features of the quark and lepton masses and KobayashiMaskawa mixing angles are explained, primarily as consequences of various aspects of SO(10) symmetry. Here the model is discussed in much greater detail. The threefold mass hierarchy as well as the relat...

1MS, PhD, Post-doctorate researcher, Department of Community Dentistry, Piracicaba Dental School, State University of Campinas, Brazil 2MSPH, PhD, Professor, Department of Community Dentistry, Piracicaba Dental School, State University of Campinas, Brazil 3MS, PhD student, Department of Morphology, Piracicaba Dental School, State University of Campinas, Brazil 4Speech Therapist, Limeira, SP, Br...

Verification of Euler / Navier-Stokes Codes using the Method of Manufactured Solutions C. J. Roy,1,*,† C. C. Nelson,2 T. M. Smith,3 and C. C. Ober3 1Aerospace Engineering Department, Auburn University, AL 36849-5338, U.S.A. 2740 Fourth St., Arnold Engineering Development Center,§ Arnold AFB, TN 37389-6001, U.S.A. 3MS 0316, Sandia National Laboratories,‡ PO Box 5800, Albuquerque, NM 87185-0316, ...

24 Peripheral nerve stimulation inhibits the motor cortex and the process has been termed 25 short latency afferent inhibition (SAI) at interstimulus intervals (ISI) of ~20 ms. The 26 objective of the present study is to test how SAI interacts with short interval intracortical 27 inhibition (SICI) under different stimulation conditions. We studied 20 healthy 28 volunteers. Surface electromyogra...

Background Type 2 diabetes mellitus has been shown to be associated cognitive decline and an increased risk of mild impairment dementia in elderly persons (Biessels et al., 2014). The aim this research was determine whether the Neurocognitive Frailty Index (NFI, Pakzad 2017) could help predict changes people with diabetes. Method Participants study were drawn from waves 1 (1991 1992) (1996 1997...

BACKGROUND Older women treated with conjugated estrogens may have an increased risk of dementia, but the effect of naturally occurring sex hormones on cognition is not certain. METHODS Bioavailable estradiol and free testosterone level were obtained from 792 (55% men, 51% black) participants. We assessed cognition with the Modified Mini-Mental State Examination (3MS), Selective Reminding Test...