Multiple mechanisms of regulation in the CDP-choline pathway for phosphatidylcholine (PC) synthesis were revealed by exploring the effects of choline and inositol on this pathway in Saccharomyces cerevisiae. At exogenous choline concentrations below 100 microM, phosphocholine cytidylyltransferase was rate-limiting; at higher choline concentrations the conversion of choline to phosphocholine by ...

BACKGROUND Preventive dental care use remains relatively low in Japan, especially among working-age adults. Universal health insurance in Japan covers curative dental care with an out-of-pocket payment limit, though its coverage of preventive dental care is limited. The aim of this study was to test the hypothesis that income inequality in dental care use is found in preventive, but not curativ...

Purpose of review: Defining the nature of the association between chronic obstructive pulmonary disease (COPD) and other chronic conditions is of primary importance to improve the health status of COPD patients through the optimal care of comorbidities. We aimed at providing a reasoned guide to understand, recognize and treat comorbidity of COPD with the perspective of shifting from comorbidity...

SUMMARY: The concern over medicolegal liability is pervasive among physicians. We sought, through an email survey to the members of the ASNR, to assess the experiencewith and attitudes about themedicolegal environment among neuroradiologists. Of 4357 physicians surveyed, 904 answered at least 1 of the questions in the survey; 449 of 904 (49.7%) had been sued: 180 (44.9%) had been sued once, 114...

The present work reports on the application and the evaluation of a multitude of crosslinking approaches including high-energy irradiation, redox-initiating systems and conventional carbodiimide-coupling chemistry for frozen and/or freeze-dried porous gelatin scaffolds. The latter is particularly relevant for a plethora of biomedical applications such as tissue engineering supports, wound dress...

The article provides lexical statistical analysis of K. Vonnegut's two novels and their Russian translations. It is found out that there happen some changes between the speed of word types and word tokens ratio change in the source and target texts. The author hypothesizes that these changes are typical for EnglishRussian translations, and moreover, they represent an example of Baker's translat...

&Adrenergic receptors were partially purified from turkey erythrocyte membranes by alpr.enolo1-agarose chromatography to 0.25-2 nmol/mg of protein, and the stimulatory guanosine 5’-triphosphate (GTP) binding protein of adenylate cyclase (G,) was purified from rabbit liver. These proteins were reconstituted into phospholipid vesicles by addition of phospholipids and removal of detergent by gel f...

Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small-cell lung cancer (NSCLC) accounting for >80% of all newly diagnosed cases of lung cancer. For patients with early-stage disease, from clinical stage IA through IIB, surgical resection represents the standard of care. However, ∼50% of those patients undergoing surgical resection will relapse and die of re...

This chapter discusses normalization of relations when the candidate keys of a relation have missing information represented by nulls. The chapter shows that problems and confusion can arise in normalizing relations with nulls in candidate keys. Candidate keys with missing information commonly are found in relations that represent information on two entities with a one-to-one relationship betwe...