Abstract In this work, lead(II) adsorption on activated carbons, tire-derived carbon (TAC), and commercial (CAC), in a packed-bed column, was simulated using the Aspen Adsorption® V11 flowsheet simulator. The simulator used to model fixed-bed column establish breakthrough curves by varying initial concentration of ions (500 mg/L, 1000 2000 3000 mg/L), bed height (0.2 m, 0.3 0.4 0.5 0.6 m), flow...

OBJECTIVES To describe the population pharmacokinetics of oral amoxicillin and to compare the PTA of current dosing regimens. METHODS Two groups, each with 14 healthy male volunteers, received oral amoxicillin/clavulanic acid tablets on two separate days 1 week apart. One group received 875/125 mg twice daily and 500/125 mg three times daily and the other group 500/125 mg twice daily and 250/...

Twenty-eight days subacute toxicity studies performed in rats using sclerotial powder of Lignosus cameronensis cultivar was conducted to assess its safety for consumption prior to other scientific investigations on its medicinal benefits, nutraceutical or pharmaceutical application of the mushroom. The study was conducted at 250, 500, and 1000 mg/kg sclerotial powder of L. cameronensis cultivar...

BACKGROUND Currently-available antidepressant agents produce various adverse effects, and are expensive. At present, various plants are being evaluated for their possible role against numerous diseases, and no doubt, the role of traditional and complementary medicines in the development of effective therapy is incredible. The present study was designed to evaluate antidepressant-like activity o...

The aim of this study was to evaluate the safety and efficacy of oral terbinafine (500 and 1000 mg day(-1)) in the treatment of cutaneous or lymphocutaneous sporotrichosis. A culture for Sporothrix schenckii was required for inclusion into this multicentre, randomized, double-blind, parallel-group study. Patients received either 250 mg b.i.d. or 500 mg b.i.d. oral terbinafine for up to a maximu...