Keloid scars, which are excessive forms of cutaneous scarring, overgrow the boundaries original wound and do not regress spontaneously. Although keloid pathogenesis has been linked to numerous dysregulated signalling pathways, underlying causes remain poorly understood. scars have shown be 10-50 times stiffer than normal skin often form in areas body where tension is high. As a result, it thoug...

CD200R is an immune receptor of the IgG family that primarily expressed on cells myeloid lineage and was recently identified as a marker for Th2 biology (Blom et al 2017). In vivo studies with knockout mice either or its ligand, CD200, have demonstrated it inhibitory capable negatively regulating responses. Previous work using agonistic antibodies to mouse showed inhibition mast cell activation...

We investigated the relationships between single nucleotide polymorphisms (SNPs) of the interleukin (IL)-6 gene 174 G>C (rs1800795), 572 G>C (rs1800796), and 597 G/A (rs1800797) and coronary artery disease (CAD) risk in a Chinese population. This case-control study recruited 296 CAD patients and 327 controls between January 2009 and May 2012. Genotyping of IL-6 174 G>C (rs1800795), 572 G>C (rs1...

BACKGROUND Pro-inflammatory cytokine gene polymorphisms are potential candidates for susceptibility for both type 2 diabetes mellitus (DM) and chronic periodontitis (CHP). This study explored the association of interleukin-1 beta (IL-1 β) +3954, interleukin-6 (IL-6) -597/-174 and tumor necrosis factor-alpha (TNF-α) -308 single nucleotide polymorphisms in CHP with and without type 2 DM in Malaya...

OBJECTIVE To describe the prevalence and risk factors for incomplete bladder emptying after midurethral slings (MUS) in a large multicenter trial. METHODS Five hundred ninety-seven women were randomized to retropubic (RMUS) or transobturator midurethral slings as part of the Trial of MidUrethral Slings study. Demographic data and voiding symptoms were obtained preoperatively along with urodyn...

BACKGROUND AND PURPOSE To assess the usefulness of transcranial Doppler sonography, we investigated the rate of blood flow signal recording failure in the middle cerebral artery in Japanese subjects. Furthermore, we studied the effect of increased emitted power on the rate of successful recording in some of the patients in whom recording failure had been detected at the standard transducer powe...