BACKGROUND Distance running performance is a viable model of human locomotion. METHODOLOGY/PRINCIPAL FINDINGS To evaluate the physiologic strain during competitions ranging from 5-100 km, we evaluated heart rate (HR) records of competitive runners (n = 211). We found evidence that: 1) physiologic strain (% of maximum HR (%HRmax)) increased in proportional manner relative to distance completed...

Aim of the study was to examine cardiorespiratory parameters at individual ventilatory threshold (IVT) and peak exercise capacity ([Formula: see text]) in outpatient diabetic and sarcopenic obese subjects. Seventeen obese subjects (BMI: 36.6 ± 4.1 kg·m(-1)) and sixteen SO subjects (BMI: 37.0 ± 7.3 kg·m(-1)) were compared with sixteen T2DM subjects (BMI: 37.7 ± 5.6 kg·m(-1)). All groups performe...

The impact of manipulating shear stress on conduit artery vasodilation has not been comprehensively described in vivo. We hypothesized that manipulation of SR through the brachial and radial arteries would be associated with corresponding changes in diameter. We performed a series of studies involving the following: (1) leg cycle exercise at increasing intensities (≈70 and 85% maximum heart rat...

Heart rate (HR) is arguably one of the most often measured physiological responses in relation to physical fitness or health. HR measured at rest, during submaximal exercise, at maximal exercise and during recovery can provide some level of assessment of fitness and health. In the past, HR was most often measured from manual palpitation of a pulse (palpation), using a stethoscope (auscultation)...

To compare the effects of 6 weeks of long or short high-intensity interval training (long- or short-HIIT) on body composition, hunger perception, food intake and rating of perceived exertion (RPE). Twenty previously untrained women (25±5 years) were randomly assigned to do a long-HIIT (n=10) or a short-HIIT (n=10). The long-HIIT group performed fifteen 1-min bouts at 90% of maximum heart rate (...

The purpose of this study was to investigate physiological responses to various intermittent and continuous small-sided games (SSGs) - including 2-a-side, 3-a-side, and 4-a-side games - in young soccer players. Twenty soccer players (average age 16.6±0.5 years; mean body height 176.2±4.6 cm; mean body mass 65.9±5.6 kg) voluntarily participated in this study. The subjects underwent anthropometri...

Low-volume, time-efficient high-intensity interval training (HIIT), which involves whole-body (WB) callisthenics exercises, has gained worldwide popularity in recent years. However, the physiological and perceptual impact of WB-HIIT comparison to specialised, equipment-based is relatively less studied. This study compared acute responses a single session WB-HIIT, ergometer-based HIIT (ERG-HIIT)...

Background: As the population ages, cognitive impairment and dementia have become one of greatest health threats in older adults. Prior studies suggest that exergaming could improve function To date, few long-term exergames intervention on adults during COVID-19 epidemic exist. This study aimed to investigate effects exergame Chinese adults, examine whether was more effective than aerobic danci...

This study aimed to prove the effect of moderate-intensity aerobic exercise on increasing Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1α) levels in obese women. A total 12 women aged 20-25, with body mass index (BMI) 25-30 kg/m2, normal systolic blood pressure, and resting heart rate as subjects study. Subjects were randomly divided into 2 groups, namely K1 (n=6; co...

BACKGROUND Therapy with racemic compounds produces effects that can be attributed to both (S)- and (R)-enantiomers. Here we have tested the hypothesis that an enantiomer-enantiomer interaction would modulate the effects of treatment with a racemate, the antiarrhythmic propafenone. Previous studies have shown that while the enantiomers of propafenone exert similar sodium channel-blocking (QRS wi...