With rising incidence of breast carcinoma in Asian population, staging workup remains a crucial entity diseasemanagement and outcome. Bone scintigraphy for detection osteoblastic metastasis has remained convenient choice.However, the presence underlying lytic bony lesions sensitivity 99mTc-MDP bone scan is questionable when comparedto 18F-FDG PET-CT scan. We present case that showed better pick...

We present a patient with Fanconi syndrome who demonstrated poor renal uptake of 99mTc-DMSA and high urinary concentration of the tracer. A 99mTc-DTPA scan was normal and the creatinine clearance only minimally decreased. These findings suggest that 99mTc-DMSA may be accumulated in the kidney by glomerular filtration and subsequent tubular reabsorption, with the nonabsorbed fraction appearing i...

OBJECTIVE The aim of this study was to compare the metabolic activity of metastatic foci from breast and prostate cancer patients as scanned by fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and by technetium-99m methyl diphosphonate (99mTc-MDP) bone scan (BS). SUBJECTS AND METHODS Forty one patients were studied, divided into 2 groups based o...

Technetium-99m radiopharmaceuticals play an important role in wide range of applications in nuclear medicine. Bone imaging agents are among the fi rst developed 99mTc-radiopharmaceuticals and the most widely used radiopharmaceuticals in diagnostic nuclear medicine [1]. Bisphosphonates (BPs) are synthetic organic compounds characterized by a P-C-P backbone structure. They are chemically stable a...