نتایج جستجو برای: aamyotrophic lateral sclerosis

تعداد نتایج: 178071  

Journal: :Journal of Physiotherapy 2013

Journal: :Brain : a journal of neurology 2016
Pauline Vercruysse Jérôme Sinniger Hajer El Oussini Jelena Scekic-Zahirovic Stéphane Dieterlé Reinhard Dengler Thomas Meyer Stephan Zierz Jan Kassubek Wilhelm Fischer Jens Dreyhaupt Torsten Grehl Andreas Hermann Julian Grosskreutz Anke Witting Ludo Van Den Bosch Odile Spreux-Varoquaux Albert C Ludolph Luc Dupuis

Amyotrophic lateral sclerosis, the most common adult-onset motor neuron disease, leads to death within 3 to 5 years after onset. Beyond progressive motor impairment, patients with amyotrophic lateral sclerosis suffer from major defects in energy metabolism, such as weight loss, which are well correlated with survival. Indeed, nutritional intervention targeting weight loss might improve survival...

Journal: :Nihon Naika Gakkai Zasshi 2013

Journal: :Mayo Clinic Proceedings 2018

Journal: :Nature Reviews Disease Primers 2017

Journal: :Frontiers in Neurology 2021

Journal: :Baylor University Medical Center Proceedings 2012

2014
Stephanie R. Shepheard Tim Chataway David W. Schultz Robert A. Rush Mary-Louise Rogers

Objective biomarkers for amyotrophic lateral sclerosis would facilitate the discovery of new treatments. The common neurotrophin receptor p75 is up regulated and the extracellular domain cleaved from injured neurons and peripheral glia in amyotrophic lateral sclerosis. We have tested the hypothesis that urinary levels of extracellular neurotrophin receptor p75 serve as a biomarker for both huma...

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