The endoplasmic reticulum stress response, also known as the unfolded protein response (UPR), has been implicated in the normal physiology of immune defense and in several disorders, including diabetes, cancer, and neurodegenerative disease. Here, we show that the apoptotic receptor CED-1 and a network of PQN/ABU proteins involved in a noncanonical UPR response are required for proper defense t...

The Materia Medica works of Rhazes, (vol2 of Canon), Al-Biruni (Kitab as -Saidana), Abu Mansur (Haqaiq al-Adwiya), Gorgani (Vol 9 and 10 of Zahira-e-Harazmsahi), Ansari Shirazi (Ihtiyarat-e-Bdi i), Hakim Mu min (Tuhfa) and Aqili Hurasani (Aqrabuzin-e Kabir) and others are the most important works of Islamic and Iranian physicians on Natural Drugs. The systematic pharmacognostical, pharmacologic...

Dietary regulation of the intestinal sodium-dependent glucose cotransporter (SGLT I ) Soraya P. Shirazi-Beechey*$, Susan M. Gribble*, I: Stuart Wood*, Patrick S. Tarpey*, R. Brian Beechey*, Jane Dyer*, Dennis Scottt and Patrick J. Barker$ *Epithelial Function and Development Group, Institute of Biological Sciences, University of Wales, Aberystwyth, Dyfed, SY23 3DD, U.K., +Division of Biochemist...

To apply run-time reconfiguration there is need for an appropriate model to understand reconfiguration. System on chip technology allowed the use of complex low gate/price new type of FPGA. Modelling reconfiguration and using Matlab tools is possible to simulate and rapid prototype vector control systems. The paper presents the reconfigurable models as introduced by Luk, Cheung, Shirazi and Ath...

A utilização de modelos matemáticos e avaliação da geoestatística determinação do domínio solo é uma estratégia importância fundamental para os planejamentos agropecuários ambientais, principalmente em áreas agricultura familiar incorporadas nos microbacias hidrográficas. Desta forma, este trabalho objetivou estimar o potencial método seleção métodos solos microbacia mapeamento dados estatístic...

A recent article by Maher et al. in GENETICS introduces an alternative approach to cell-type-specific gene knockdown in Caenorhabditis elegans, using nonsense-mediated decay. This strategy has the potential to be applicable to other organisms (this strategy requires that animals can survive without nonsense-mediated decay-not all can). This Primer article provides a guide and resource for educa...

(Maher 2012) introduced an approach for relative expressiveness of defeasible logics, and two notions of relative expressiveness were investigated. Using the first of these definitions of relative expressiveness, we show that all the defeasible logics in the DL framework are equally expressive under this formulation of relative expressiveness. The second formulation of relative expressiveness i...

1.—Composite Materials and Mechanics Laboratory, Department of Mechanical and Aerospace Engineering, New York University Tandon School of Engineering, Brooklyn, NY 11201, USA. 2.—Department of Computer Science and Engineering, New York University Tandon School of Engineering, Brooklyn, NY 11201, USA. 3.—Engineering Division, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates. 4.—Dep...

A high degree of diversity noted in the Neolithic mandibles from Abu Hureyra provided the opportunity to address the problem of the meaning and origin of variability in the population. Mandible morphology is approached bearing in mind cranio-facial interactions. Two morphological patterns were identified in the Abu Hureyra mandible sample. e ABU morph represents the majority, while the ABO mor...

The Materia Medica works of Rhazes, (vol2 of Canon), Al-Biruni (Kitab as -Saidana), Abu Mansur (Haqaiq al-Adwiya), Gorgani (Vol 9 and 10 of Zahira-e-Harazmsahi), Ansari Shirazi (Ihtiyarat-e-Bdi i), Hakim Mu min (Tuhfa) and Aqili Hurasani (Aqrabuzin-e Kabir) and others are the most important works of Islamic and Iranian physicians on Natural Drugs. The systematic pharmacognostical, pharmacologic...