نتایج جستجو برای: accelerated ageing

تعداد نتایج: 84954  

2016
Laurentiu Marius Dumitran Radu Setnescu Petru V. Notingher Laurentiu Viorel Badicu

Large amounts of mineral oil are used in electrical equipments as insulation and cooling medium. To avoid damages and cut-off of power electricity supply it is necessary to evaluate the mineral oil condition. Lifetime estimation of mineral oil which is based on accelerated thermal ageing at three temperatures (according to IEC 60216-1/2001) requires a long experimental time. This standardized m...

Journal: :Nature Reviews Gastroenterology & Hepatology 2010

Journal: :Gerontology 2014
Yoko Honda Shuji Honda Marco Narici Nathaniel J Szewczyk

The prospect of space travel continues to capture the imagination. Several competing companies are now promising flights for the general population. Previously, it was recognized that many of the physiological changes that occur with spaceflight are similar to those seen with normal ageing. This led to the notion that spaceflight can be used as a model of accelerated ageing and raised concerns ...

Journal: :Mutation research 2011
Alex A Freitas João Pedro de Magalhães

Given the central role of DNA in life, and how ageing can be seen as the gradual and irreversible breakdown of living systems, the idea that damage to the DNA is the crucial cause of ageing remains a powerful one. DNA damage and mutations of different types clearly accumulate with age in mammalian tissues. Human progeroid syndromes resulting in what appears to be accelerated ageing have been li...

2014
Radha B. N K. Bhanuprakash Pandurange Gowda B. K. Ramachandrappa

Seed ageing is influenced by two environmental factors, RH and temperature. The deterioration of the stored seed is a natural phenomenon and the seeds tend to lose viability even under ideal storage conditions. Accelerated ageing has been recognized as a good predictor of the storability of seed lots. Aged seeds show decreased vigour and produce weak seedlings that are unable to survive once re...

Journal: :Journal of internal medicine 2008
D B Lombard B Schwer F W Alt R Mostoslavsky

Ageing, or increased mortality with time, coupled with physiologic decline, is a nearly universal yet poorly understood biological phenomenon. Studies in model organisms suggest that two conserved pathways modulate longevity: DNA damage repair and Insulin/Igf1-like signalling. In addition, homologs of yeast Sir2--the sirtuins--regulate lifespan in diverse organisms. Here, we focus on one partic...

2012
R. Farhadi M. R. Rahmani M. Sadeghi

The effect of accelerated aging (AA) was studied in Basil (Ociumum basilicm L.) seeds. The objective of this research was to evaluate Effect of seed ageing on germination of Basil Seeds in Roodan University in year 2012. experiment was CRD design with 3 replicate. The seeds were artificially aged at 45°C and 100% relative humidity for 24, 48, 72, and 96 hours. Results indicated germination perc...

2014
Gang Guo Qiwu Shi Yanbing Luo Rangrang Fan Liangxue Zhou Zhiyong Qian Jie Yu

This study investigated ageing-resistant properties of carboxyl-terminated polyester (polyethylene glycol terephthalate) composites modified with nanoscale titanium dioxide particles (nano-TiO2). The nano-TiO2 was pretreated by a dry coating method, with aluminate coupling agent as a functional grafting additive. The agglomeration resistance was evaluated, which exhibited significant improvemen...

2011
Young Sam Seo Eun Yu Kim Woo Taek Kim

Lipid-derived molecules produced by acylhydrolases play important roles in the regulation of diverse cellular functions in plants. In Arabidopsis, the DAD1-like phospholipase A1 family consists of 12 members, all of which possess a lipase 3 domain. In this study, the biochemical and cellular functions of AtDLAH, an Arabidopsis thaliana DAD1-like acylhydrolase, were examined. Bacterially express...

Journal: :Ecology letters 2014
Jelle J Boonekamp Martijn Salomons Sandra Bouwhuis Cor Dijkstra Simon Verhulst

Optimality theories of ageing predict that the balance between reproductive effort and somatic maintenance determines the rate of ageing. Laboratory studies find that increased reproductive effort shortens lifespan, but through increased short-term mortality rather than ageing. In contrast, high fecundity in early life is associated with accelerated senescence in free-living vertebrates, but th...

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