Acellular matrices produced by tissue decellularisation are reported to have integrative properties. We examined the potential for incorporating acellular matrix grafts during procedures where there is an inadequate natural bed support enduring surgical repair. Hypospadias a common congenital defect requiring surgery, but associated with long-term complications due deficiencies in quality and q...

BACKGROUND Abdominal wall repair can be performed with synthetic or biological materials. Biological materials may reduce the risk of infections and fibrosis. The aim of this study was to evaluate two acellular human dermis products. MATERIALS AND METHODS A rat model was used to compare the two materials. One was prepared using low concentrations of NaOH; the other material was SureDerm, whic...

BACKGROUND Acellular matrices have been successfully used to heal indolent diabetic foot ulcers (DFUs). These tissues include allogenic dermis as well as xenograft dermis, pericardium, and small intestine submucosa. While all of these tissues show promise for healing DFUs, dermal-derived matrices have shown considerable potential. MATERIALS AND METHODS The authors retrospectively reviewed hea...

Neurosurgical Division of the Hospital Geral Santa Isabel, João Pessoa PB, Brazil;Associated Physician. The true importance of performing a watertight dural closure, for neurological procedures, is to avoid several complications such as cerebrospinal fluid (CSF) leakage, pseudomeningocele (PSM), meningitis, cerebral abscess, tonsilar herniation, hydrocephalus, etc. A variety of materials has be...

1. Belloste, Augustin. The Hospital Surgeon: Or, A New, Gentle, and Easie Way to Cure Speedily all Sorts of Wounds, and other Diseases Belonging to Surgery, Also A Discourse on Discovered Bones, 3rd edition, London 1713: 70–76. 2. Komorowska-Timek, E, Gabriel, A., Bennett, D.C. et al. Artificial Dermis as an Alternative for Coverage of Complex Scalp Defects following Excision of Malignant Tumor...

Objective: Benchtop methods were evaluated for preclinical inflammation/capsule formation correlation following implantation of human acellular dermal matrices. Methods: Dermal matrices were compared with native dermis for structure (histology, scanning electron microscopy), collagen solubility (hydroxyproline), enzymatic susceptibility (collagenase), and thermal stability (differential scannin...

We present reconstruction of a complicated scalp-dura defect using acellular human dermis and latissimus dorsi myocutaneous free flap. A 62-year-old female had previously undergone decompressive craniectomy for intracranial hemorrhage. The cranial bone flap was cryopreserved and restored to the original location subsequently, but necessitated removal for a methicillin-resistant Staphylococcal i...