Microglia is the effector cell of the innate immune system in central nervous system (CNS). These cells mediate inflammatory responses in injuries. Besides external factors, microglial function is also controlled by internal factors, including epigenetic regulations. Mechanisms of epigenetic regulation mainly consist of DNA methylation, histone modifications and use of non-coding RNAs. Recent s...

The linker histones (H1 or H5) which play a key role in the folding of chromatin, are general repressors of gene expression. Nuclei of the mature chicken erythrocytes (and in some mammalian cells) contain both of them. Although the interaction of H5 with DNA is stronger than that of H1, it does not prevent the transcription of some erythroid-specific genes. It has been shown that some modificat...

Descriptions of methods and results experiments on the preservation geometry dimensional parameters compressed wood using chemical physical are given. Wide ranges substances were used as stabilizers in urea aqueous solution (plasticizer during pressing). Wood treatment with ultrasound, liquid nitrogen pulsed magnetic field was methods. Urotropine, urea-formaldehyde oligomer, phenol-formaldehyde...

this research was conducted to investigate the effect of acetylation on weathering resistance of solid wood and particleboard produced from acetylated particles of fagus orientalis. after 12 hours soaking in acetic unhydride, in order to achieve three levels of weight gain, 5, 9 and 16%, acetylated particles of bech wood were heated in oven at 120oc for 30, 90 and 240 minutes, respectively. als...

The use of in situ generated (NHC)-Ni catalytic species (NHC = N-heterocyclic carbene) allows for the synthesis, in short reaction times, of a variety of tertiary alcohols from secondary alcohols through a domino oxidation-addition protocol.

oniom calculation is carried out to estimate the acidity of five aliphatic alcohols before and after adsorbing on the tip of (8,0) single-walled carbon nanotube. the oniom method is performed using a combination of density functional theory and am1 semiemperical method for alcohols and their corresponding conjugated bases. deprotonation gibbs free energies of alcohols are calculated and compare...