The hexane-1,6-diammonium cation of the title compound, C(6)H(18)N(2) (2+)·2NO(3) (-), lies across a crystallographic inversion centre and shows significant deviation from planarity in the hydro-carbon chain. This is evident from the torsion angle of -64.0°(2) along the N-C-C-C bond and thse torsion angle of -67.1°(2) along the C-C-C-C bonds. An intricate three-dimensional hydrogen-bonding netw...

Current studies were performed to overview the phytochemistry, nutritional and medicinal value of Ziziphus mauritiana (commonly known as Ber in Pakistan). The leaves Z. are comprised proteins, amino acids, alkaloids, terpenoids, fibers, flavonoids, tannins, glycosides, phenolic compounds. leave majorly demonstrate presence α-linolenic acid, plamitic acid methyl stearate n-hexane, chloroform met...

The exact role of the central acidic domain of Mdm2 in p53 degradation remains unclear. We therefore performed a systematic and comprehensive analysis of the acidic domain using a series of short deletions and found that only a minor part of the domain was indispensable for Mdm2-mediated p53 ubiquitylation. Moreover, we identified a short stretch of acidic amino acids required for p53 degradati...

CONTEXT Scyphiphora hydrophyllacea is a shrub mangrove plant of the family Rubiaceae and not yet been studied for anti-hepatocarcinogenic effects. OBJECTIVES We investigated possible in vitro anti-hepatocarcinogenic and antioxidant properties of S. hydrophyllacea. MATERIALS AND METHODS Dried leaves of S. hydrophyllacea were sequentially extracted into hexane, chloroform, ethyl acetate, and ...

In this study, the 4-week oral toxicity and anti-cancer activity of the hexane layer of Melia azedarach L. var. japonica Makino's bark extract were investigated. We carried out a hollow fiber (HF) assay and 28- day repeated toxicity study to confirm the anti-cancer effect and safety of the hexane layer. The HF assay was carried out using an A549 human adenocarcinoma cell via intraperitoneal (IP...

± S.E.)6) was chromatographed on a silica gel colurnn to separate it into the 100% hexane, 20% AcOEtl hexane, 50% AcOEtlhexane and 100% AcOEt frs. The bioassay results clearly confirmed that the active component(s) in the original hexane fr. were concentrated in the 20% AcOEtfhexane fr. (92,4%± 1.6). The activities of the other frs. were as follows: 100% hexane fr. (O.O%± O.O), 50% AcOEt!hexane...

A detailed characterization of the microemulsion composition is necessary to make the phosphorimetry suitable as powerful analytical methodology. Four microemulsion systems (hexane/n-butanol/SDS/water, hexane/n-pentanol/SDS/water, hexane/3-pentanol/SDS/ water, and hexane/n-hexanol/SDS/water) were studied, establishing the oil/water (O/W) microemulsion composition with best phosphorimetric chara...