multiple sclerosis is an inflammatory disease of the central nervous system in which t cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. the recent advances in stem cell therapies may serve as potential treatments for neurological disorders. there are broad types of stem cells such as neural, embryonic, mesenchymal and hem...

Liver biopsies from 86 patients with serologically established acute hepatitis A were evaluated for quantitative and qualitative light microscopic features together with biopsies from 78 patients with acute hepatitis type B and 76 patients with acute hepatitis type non-A, non-B. Hepatitis A was characterised by more pronounced portal inflammation than hepatitis non-A, non-B (p less than 0.01) b...

germline and somatic stem cells are distinct types of stem cells that are dedicated to reproduction and somatic tissue regeneration, respectively. germline stem cells (gscs), which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. we developed a strategy for the establishment of germline st...

An acromegalic man aged 70 developed progressive polyneuropathy affecting mainly the extremities. The peripheral nerves showed hypertrophic neuropathy and accumulation of acid mucopolysaccharides in the nerve without `onion bulb' formation. The myelin showed a lamellar disintegration and vesicular formation. It is suggested that the association of these findings represents a pathological entity...

Hepatocellular adenomas (HCAs) are uncommon, benign hepatocellular neoplasms that commonly occur in young women. Recent advances in pathology and cytogenetics have thrown fresh light on the pathogenesis of HCAs leading to classification of HCAs into 3 distinct subtypes, each with a characteristic epidemiology, histopathology, oncogenesis, and imaging findings. The aim of the article was to prov...

background and aims: natural killer t (nkt) cells have been suggested to play critical roles in a wide range of immune responses especially against hepatotropic pathogens such as hepatitis c virus (hcv). in  the  present  study,  we  investigated  the  status  of  nkt  cells  by producing interleukin-17 cytokine in  peripheral  blood.  patients and methods: as case-control study, 15 patients wi...

The acidophilic archaeons are a group of single-celled microorganisms that flourish in hot acid springs (usually pH < 3) but maintain their internal pH near neutral. Although there is a lack of direct evidence, the abundance of sugar modifications on the cell surface has been suggested to provide the acidophiles with protection against proton invasion. In this study, a hydroxyl (OH)-rich polyme...

Here, we report the draft genome sequence of "Acidibacillus ferrooxidans" strain ITV01, a ferrous iron- and sulfide-mineral-oxidizing, obligate heterotrophic, and acidophilic bacterium affiliated with the phylum Firmicutes. Strain ITV01 was isolated from neutral drainage from a low-grade chalcopyrite from a mine in northern Brazil.

BACKGROUND AND AIMS Primary aim of the present study was the evaluation of efficacy and safety of endoscopic polypectomy in a tertiary advanced endoscopic laboratory in Northwestern Greece. Additional aim was to estimate the effectiveness of endoscopic treatment of colorectal polyps and record the clinical course. METHODS One hundred and fifty consecutive patients (97 men) with colorectal pol...