traumatic brain injury (tbi) is an important clinical problem in the worldwide and especially due to breaking driving rules in iran, but undesirable consequences of trauma can persist for the rest of patient’s life. we investigated the effect of a novel weight drop model of tbi on incidence of seizure 2 weeks after tbi. in this regard, 21 male wistar rat weighted 250-300 gr randomly were divide...

Introduction: This study was aimed to investigate the beneficial effects of functional magnetic resonance imaging (fMRI) data in treatment planning for patients with CNS tumors in order to decrease the injury of functional regions of the brain followed by increase in life quality and survival of patients. This study pursues a novel approach in planning for the treatment of brai...

patients and methods the study was performed on 40 tbi patients referred to the shahid beheshti hospital of kashan city and 40 normal controls in kashan. traumatic brain injured patients and normal controls were selected by convenience sampling. two groups filled out the demographic sheet, cognitive failures questionnaire (cfq) and meta-cognitions questionnaire 30 (mcq-30). the data were analyz...

in the mammalian, there are three ncx genes (ncx1, ncx2, ncx3), which their three proteins are differentially expressed in distinct regions of the central nervous system, where they might underlie different physiological and pathophysiological functions. ncx is a nine-transmembrane protein which is distributed in the brain widely. ncx operates in a bidirectional way, and exchanges ca2+ and na+ ...

conclusions increased serum levels of interleukins 6 and 8 as a predictive marker might be associated with unfavorable clinical outcome in patients with severe tbi. results comparing the serum levels of interleukins in two groups with favorable and unfavorable clinical outcomes showed that the mean serum levels of interleukins 6 and 8 in group with favorable outcome was 85.2 ± 51.6 and 52.2 ± 3...

Behavior! When most people associate behavior with acquired brain injury (ABI) they identify problems; problems ranging from aggression and agitation to non-compliance and depression (Baguley, Cooper, Felmingham, 2006; Jorge, Robinson, Moser, Tateno, Crespo-Facorro, Arndt, 2004; Kim, 2002). Requested treatment goals often focus on the cessation of aberrant actions on the part of the individual,...

Improvements over recent decades in acute care of the brain-injured now ensure that all but the most severely injured survive. The legacy of that survival is an increasing number of people with enduring organic mental disorders. Here, I will focus upon the psychiatric sequelae of five types of severe singleinsult brain injury: head trauma, subarachnoid haemorrhage, and hypoxic, hypoglycaemic an...

Language impairments in patients with acquired brain injury can have a negative impact on social life as well as on other cognitive domains. Discourse impairments are among the most commonly reported communication deficits among patients with acquired brain damage. Despite advances in the development of diagnostic tools for detecting such impairments, few studies have investigated interventions...

OBJECTIVE The purpose of this review was to investigate the efficacy of rehabilitation interventions in acquired brain injury (ABI) rehabilitation to provide guidance for clinical practice based on the best available evidence. METHODS AND MAIN OUTCOMES A systematic review of the literature from 1980-2005 was conducted focusing on rehabilitation interventions for ABI. The efficacy of a given i...