Mouse hepatitis virus (MHV), a member of the Coronaviridae, contains a polyadenylated positive-sense single-stranded genomic RNA which is 31 kb long. MHV replication and transcription take place via the synthesis of negative-strand RNA intermediates from a positive-strand genomic template. A cis-acting element previously identified in the 3' untranslated region binds to trans-acting host factor...

A 2D finite element model for the solution of wave equations is developed. The fluid is considered as incompressible and irrotational. This is a difficult mathematical problem to solve numerically as well as analytically because the condition of the dynamic boundary (Bernoulli’s equation) on the free surface is not fixed and varies with time. The finite element technique is applied to solve non...

Hypophosphatemia leads to an increase in Na-Pi co-transporter (NaPi-2) mRNA levels. This increase is post-transcriptional and correlates with a more stable transcript mediated by the terminal 698 nt of the NaPi-2mRNA. A 71 nt binding element was identified using renal proteins from rats fed control and low Pi diet. The binding of (–) Pi renal proteins to this transcript was increased compared t...