The Bidomain model is nowadays one of the most accurate mathematical descriptions of the action potential propagation in the heart. However, its numerical approximation is in general fairly expensive as a consequences of the mathematical features of this system. In this paper we analyze an Optimized Schwarz approach for the numerical solution of the Bidomain problem. The convergence of the iter...

We study cardiac action potential propagation under severe reduction in gap junction conductance. We use a mathematical model of cellular electrical activity that takes into account both three-dimensional geometry and ionic concentration effects. Certain anatomical and biophysical parameters are varied to see their impact on cardiac action potential conduction velocity. This study uncovers quan...

Retinal amacrine cells are interneurons that make lateral and vertical connections in the inner plexiform layer of the retina. Amacrine cells do not possess a long axon, and this morphological feature is the origin of their naming. Their dendrites function as both presynaptic and postsynaptic sites. Half of all amacrine cells are GABAergic inhibitory neurons that mediate lateral inhibition, and...