PURPOSE Accumulating evidence has shown that dysregulation of microRNA-191 (miR-191) is closely associated with tumorigenesis and progression in a wide range of cancers. This study aimed to explore the potential role of miR-191 in esophageal squamous cell carcinoma (ESCC). MATERIALS AND METHODS miR-191 expression was assessed in 93 ESCC tissue specimens by real-time polymerase chain reaction,...

APPLICABILITY OF NORMAL FORMS IN HYPERLINK DATABASE STRUCTURE

In our study we assume that the latency of food safety policy making renders the issue an ideal case to study the mobilization by challenger organization through the Internet. By analyzing online issue networks in the field of food safety in the UK, the US, Germany and Switzerland we seek to reveal food safety issue networks in the Internet and determine the dominant actors and coalitions. We d...

Wireless Networks have been the topic of fundamental research in recent years with the aim of achieving reliable and efficient communications. However, due to their complexity, there are still many aspects of such configurations that remain as open problems. The focus of this thesis is to investigate some throughput limits of wireless networks. The network under consideration consists of n sour...

CONTEXT Well-differentiated thyroid carcinomas include papillary (PTC) and follicular (FTC) carcinomas. FTC is usually a more aggressive form of cancer than the more common papillary type. miR-191 expression is frequently altered in several neoplasias, being up-regulated in some cases, such as pancreatic carcinomas, and down-regulated in other carcinomas, such as melanomas. OBJECTIVE The obje...

BACKGROUND Although aberrant expression of several miRNAs was found during the pathological development of endometriosis to endometriosis-associated ovarian cancer (EAOC), their roles are not fully understood. miR-191 is a miRNA significantly upregulated in endometriosis and EAOC patients. However, its downstream network is still not clear. This study explored its role in malignant transformati...

The COVID-19 pandemic created a unique climate for examining the links between stressful conditions and couples’ relationship well-being. According to theories of stress spillover, stressors originating outside relationship, such as work financial uncertainty, often undermine quality. However, if individuals can easily attribute their problems circumstances, may be more resilient. Given salienc...

Crystal structures of the complexes formed between cytochrome c peroxidase and cyanide, nitric oxide, carbon monoxide, and fluoride have been determined and refined to 1.85 A. In all four complexes significant changes occur in the distal heme pocket due to movement of Arg-48, His-52, and a rearrangement of active site water molecules. In the cyanide, nitric oxide, and carbon monoxide complexes,...

Crystal structures of the complexes formed between cytochrome c peroxidase and cyanide, nitric oxide, carbon monoxide, apd fluoride have been determined and refined to 1.85 A. In all four complexes significant changes occur in the distal heme pocket due to movement of Arg-48, His-52, and a rearrangement of active site water molecules. In the cyanide, nitric oxide, and carbon monoxide complexes,...