Introduction: Some recent studies have shown that citicoline improves clinical symptoms in patients with stroke. Citicoline's mechanism of action in improving the clinical symptoms is not recognized yet. The aim of this study was to evaluate the cerebrovascular hemodynamic status in patients with ischemic stroke treated with citicoline compared with the control group. <st...

Rapid diagnosis and timely treatment improves the outcome in patients with ischemic stroke, but a rapid and sensitive blood test for ischemic stroke does not exist. This study tested whether a panel of biomarkers might be useful in the diagnosis of acute ischemic stroke. Consecutive patients with suspected stroke presenting to the emergency department of a university hospital in Korea were enro...

background: serum troponin elevation, characteristic of ischemic myocardial injury, has been observed in some acute ischemic stroke (ais) patients. its cause and significance are still controversial. the purpose of this study is to find determinants of troponin elevation and its relationship with stroke severity and location. methods: between january 2013 and august 2013, 114 consecutive ais pa...

STUDY OBJECTIVE Little is known about the presenting features of acute ischemic and hemorrhagic stroke in children presenting to the emergency department (ED). Yet, initial clinical assessment is a key step in the management pathway of stroke. We describe the presentation in the ED of children with confirmed acute ischemic and hemorrhagic stroke subtypes. METHODS We conducted a retrospective ...

background & aim: stroke in young adults is rare but can be devastating for the affected individuals and their families. some triggers of stroke may be acute but transient effects on the pathophysiological condition while other factors may be effective overa longer period. methods & materials: this study was a case-crossover study on 18 young adults. the study included patients aged 15-49 years...

OBJECTIVE To study prognostic characteristics of cardiac troponin I (cTnI) elevation in acute ischemic stroke. METHODS We retrospectively studied patients (n = 248) with acute ischemic stroke, acute ST-segment elevation myocardial infarction, and acute non-ST-elevation myocardial infarction who were treated between January 2013 and October 2015. Baseline demographic data and changes in cTnI l...

BACKGROUND Acute ischemic stroke is a major cause of mortality and morbidity in Taiwan. Diffusion-weighted image (DWI) is a sensitive and common strategy used for imaging acute ischemic stroke. CASE REPORT We present a case of a negative DWI MRI for detecting acute ischemic stroke in a clinical setting. A 75-year-old male had a DWI performed after onset of symptoms suggesting acute ischemic str...

 Background: The role of uric acid as a risk factor for vascular disease and acute stroke is controversial and there is little information about it. In this study, we determined serum uric acid levels in patients with acute stroke and assessed its relationship with cerebrovascular risk factors. Methods: In this cross sectional study, we assessed patients with acute stroke who were admitted in F...

The concept of using t-PA for the treatment of acute ischemic stroke became a reality in the mid-1980s when research began via the National Institute of Neurological Disorders and Stroke (NINDS) Pilot Studies Program. Indeed, the first patient with acute ischemic stroke treated with t-PA in a clinical trial setting was performed by members of the Greater Cincinnati/Northern Kentucky Stroke team...