VALID AND RELIABLE DEFINItions are essential to conduct epidemiological studies successful ly and to facilitate enrollment of a consistent patient phenotype into clinical trials. Clinicians also need such definitions to implement the results of clinical trials, discuss prognosis with families, and plan resource allocation. Following the initial description of acute respiratory distress syndrome...

Submit Manuscript | http://medcraveonline.com First described by Ashbaugh in 1967, ARDS was observed in combat patients who developed respiratory distress, diffuse lung infiltrates, and respiratory failure despite oxygen therapy after occurrence of nonthoracic injuries, severe pancreatitis, massive transfusions, sepsis and various other insults [2]. As compared to decades ago, today, clinicians...

ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) is a clinical condition characterized by impaired gas exchange as a result of the accumulation of edema in the alveolar space. The clinical management of ARDS patients includes mechanical ventilation with high oxygen concentrations. Mechanical ventilation alleviates the work of breathing and hypoxemia while allowing time for the lungs to recover from t...

VALID AND RELIABLE DEFINItions are essential to conduct epidemiological studies successful ly and to facilitate enrollment of a consistent patient phenotype into clinical trials. Clinicians also need such definitions to implement the results of clinical trials, discuss prognosis with families, and plan resource allocation. Following the initial description of acute respiratory distress syndrome...

Acute respiratory distress syndrome is a disease of acute onset characterized by hypoxemia and infiltrates on chest radiographs that affects both adults and children of all ages. It is an important cause of respiratory failure in pediatric intensive care units and is associated with significant morbidity and mortality. Nevertheless, until recently, the definitions and diagnostic criteria for ac...

Background: Wasp stings usually cause local reactions such as itching, urticaria, angioedema and anaphylaxis. Life-threatening complications following multiple wasp stings are relatively rare and unexpected. However, rhabdomyolysis and acute respiratory distress syndrome following wasp stings are possible. Case presentation: A middle-aged male worker was stung by a swarm of wasps all over his b...

CONTEXT The acute lung injury and acute respiratory distress syndrome are critical illnesses associated with significant morbidity and mortality. Mechanical ventilation is the cornerstone of supportive therapy. However, despite several important advances, the optimal strategy for ventilation and adjunctive therapies for patients with acute lung injury and acute respiratory distress syndrome is ...

OBJECTIVES To identify a novel, generalizable diagnostic for acute respiratory distress syndrome using whole-blood gene expression arrays from multiple acute respiratory distress syndrome cohorts of varying etiologies. DATA SOURCES We performed a systematic search for human whole-blood gene expression arrays of acute respiratory distress syndrome in National Institutes of Health Gene Expressi...