This paper discusses the development of a distributed asynchronous atomic action scheme for Ada 95. The scheme makes use of many unique Ada 95 features including protected objects, asynchronous transfer of control and the Distributed Systems Annex. We present the packages which implement the local and global action support and illustrate their use in a (partial) implementation of the FZI Produc...

-This paper reviews the concepts of a theory of modelling and simulation that relate to the validation enterprise. The theory provides a vocabulary, concepts, and mathematically rigorous tools with which to tackle problems in simulation model validation. We have implemented a hierarchical, distributed, object-oriented, and knowledge-based modelling and simulation environment in Ada. The environ...

This paper describes an implementation of Linda for Ada 95. The new capabilities of object oriented programming and programming by extension are used to define an elegant, type safe and easy to use interface to Linda. The implementation provides more of the functionality of Linda than Ada-Linda for Ada 83. A short presentation of the Linda model and a programming example are also included.

Adenosine deaminase (ADA) is an important regulator of insulin action. The single nucleotide polymorphism (SNP) G22A in the ADA gene decreases enzymatic activity of ADA. The aim of this study was to investigate the relationship between the SNP G22A and blood glycemic control, insulin resistance, and obesity of gestational diabetes mellitus (GDM) patients in an Iranian population. SNP G22A was d...

The Ada language has been designed to support development of concurrent and distributed software. While the Ada-83 standard de®ned the basic mechanisms of rendezvous-based tasking, the Ada-95 standard signi®cantly extended this capability with the introduction of several advanced tasking constructs. We present and discuss formal models of these key tasking constructs using the Petri net model. ...

Enhanced central nervous system (CNS) delivery of certain poorly penetrating 2',3'-dideoxynucleosides has been achieved by designing prodrugs that are substrates for enzymes, such as adenosine deaminase (ADA), that are present at high activities in brain tissue. In this study, the potential role of adenosine deaminase localized within the endothelial cells of the blood-brain barrier (BBB) in pr...

This article presents ERB, the ESA Ravenscar Benchmark. ERB aims at providing a synthetic benchmark comparing the efficiency of various Ada Ravenscar implementations and the RTEMS C implementation featuring the native threading model. ERB is original compared to existing Ada benchmarks, such as the ACES or the PIWG, not only because it is the first Ada Ravenscar benchmark, but also because it p...

While the Distributed Systems Annex of Ada 95 provides developers with a framework for easy contruction of safe distributed systems, integrating distribution seamlessly in the strong typing and well-defined semantics of Ada, it lacks the cross-platform, multiple-languages capabilities offered by CORBA. This paper presents CIAO (CORBA Interface for Ada distributed Objects), a tool for automated ...

Adenophostin A (AdA) is a potent agonist of the d-myo-inositol 1,4,5-trisphosphate receptor (Ins(1,4,5)P3R). Various 2-aminopurine analogues of AdA were synthesized, all of which (guanophostin 5, 2,6-diaminopurinophostin 6, 2-aminopurinophostin 7, and chlorophostin 8) are more potent than 2-methoxy-N6-methyl AdA, the only benchmark of this class. The 2-amino-6-chloropurine nucleoside 11, from V...

Over the years, number of design methodologies were developed. One of the state-of-the-art modeling approaches is Model Driven Architecture. This thesis is an attempt to utilize the MDA in a specific and complex domain – real-time systems development. In MDA framework there are three levels of abstraction: computation independent, platform independent and platform specific. The target environme...