1. The liberation of ammonia from adenosine 5'-phosphate (AMP) and adenosine and the release of inorganic phosphate from AMP were investigated in homogenates of bovine and human parotid glands. 2. Adenosine phosphate deaminase (AMP deaminase) was purified from bovine and human parotid glands. The enzyme preparations obtained were free from adenosine deaminase and 5'-nucleotidase activities. 3. ...

The RNA editing occurring in plant organellar genomes mainly involves the change of cytidine to uridine. This process involves a deamination reaction, with cytidine deaminase as the catalyst. Pentatricopeptide repeat (PPR) proteins with a C-terminal DYW domain are reportedly associated with cytidine deamination, similar to members of the deaminase superfamily. PPR genes are involved in many cel...

Keywords Disease name and synonyms AMP deaminase AMP deaminase deficiency Diagnosis criteria-definition Differential diagnosis Prevalence Clinical description Management Etiology Diagnostic methods Unresolved questions References Abstract There are two types of adenosine monophosphate deaminase deficiency. Myoadenylate deaminase deficiency is an inherited disorder of muscular energy metabolism ...

Ethylene inhibits nodulation in various legumes. In order to investigate strategies employed by Rhizobium to regulate nodulation, the 1-aminocyclopropane-1-carboxylate (ACC) deaminase gene was isolated and characterized from one of the ACC deaminase-producing rhizobia, Rhizobium leguminosarum bv. viciae 128C53K. ACC deaminase degrades ACC, the immediate precursor of ethylene in higher plants. T...

In most instances, marked deficiency of the purine catabolic enzyme adenosine deaminase results in lymphopenia and severe combined immunodeficiency disease. Over a 2-yr period, we studied a white male child with markedly deficient erythrocyte and lymphocyte adenosine deaminase activity and normal immune function. We have documented that (a) adenosine deaminase activity and immunoreactive protei...

the effect of physiological concentrations of caffeine (purified from persian tea) on adenosine deaminase (ada) activity at physiological and pathological concentrations of adenosine (as substrate) in 50 mm tris-hcl buffer (ph 7.3) at 37°c was investigated, using uv-vis spectroscopy. ada exhibited a bi-phasic activity behavior and both phases showed positive cooperativities indicating adenosine...

conclusions serum ada activity with high specificity percentage may be a useful alternative test in restricted resource areas to rule out diagnosis of ptb. however, serum ada activity is not a useful tool for tb diagnosis. mean serum ada level in the ptb group was clearly higher than the mean serum ada in the other three groups. mean serum ada was 26 iu/l in ptb patients, 19.48 iu/l in patients...

A previously cloned partial adenosine deaminase cDNA insert (0.8 kilobase) was used to clone additional nucleotide sequences from human HPB ALL cDNA libraries. cDNA encompassing the entire coding, and 3'-untranslated regions as well as nearly all of the 5'-untranslated region was obtained. The complete amino acid sequence of the enzyme deduced from the cDNA sequence and protein sequencing consi...

abstract in this study a greenhouse experiment was conducted to evaluate the role of acc deaminase enzyme on alleviation of salinity stress of canola plant. canola plants were exposed to pseudomonas fluorescens strain p12 which contains a rhizobacter capable of producing pseudomonas fluorescens in comparison with plants exposed to mutant pm12 unable to produce the required enzyme. the mutant wa...

we describe the development of enterovirus meningoencephalitis associated with increased adenosine deaminase in cerebrospinal fluid of a 12-year-old boy, a known case of hypogamaglobulinemia despite monthly replacement of ivig. the patient was referred to our center with fever, headache and vomiting for 10 days. csf analysis was compatible with aseptic meningoencephalitis but high csf protein (...