OBJECTIVES This study sought to assess the cost-effectiveness of captopril therapy for survivors of myocardial infarction. BACKGROUND The recent randomized, controlled Survival and Ventricular Enlargement (SAVE) trial showed that captopril therapy improves survival in survivors of myocardial infarction with an ejection fraction < or = 40%. The present ancillary study was designed to determine...

OBJECTIVE To assess whether revascularisation that is considered to be clinically appropriate is also cost effective. DESIGN Prospective observational study comparing cost effectiveness of coronary artery bypass grafting, percutaneous coronary intervention, or medical management within groups of patients rated as appropriate for revascularisation. SETTING Three tertiary care centres in Lond...

objectives : to estimate the disabled-adjusted life years ( dalys) of road traffic accidents in patients referred to hospitals in yazd province, central iran. methods: this cross-sectional study was conducted in yazd province during 2010. to calculate the years of life lost (yll) due to premature death and to calculate the incidence of non-fatal injuries and years lost due to disability (yld), ...

OBJECTIVE To analyze the cost-utility of using extracorporeal oxygenation for patients with severe acute respiratory distress syndrome in Brazil. METHODS A decision tree was constructed using databases from previously published studies. Costs were taken from the average price paid by the Brazilian Unified Health System (Sistema Único de Saúde; SUS) over three months in 2011. Using the data of...

Five percent of all pregnant women and 25% of pregnant women with insulin-dependent diabetes mellitus (IDDM) develop postpartum thyroiditis (PPT) during the first year after delivery. PPT has significant morbidity and can be predicted prenatally by the presence of thyroid peroxidase (TPO) antibody. Our objective was to estimate the cost-effectiveness of screening pregnant women for the TPO anti...

BACKGROUND The objective of the study was to analyse whether azacitidine is a cost-effective option for the treatment of myelodysplastic syndrome in the Spanish setting compared with conventional care regimens, including best supportive care, low dose chemotherapy and standard dose chemotherapy. METHODS A life-time Markov model was constructed to evaluate the cost-effectiveness of azacitidine...