allowing it to cool ; the undissolved chloretone will separate from the liquid and the resultant solution will contain about 1% of chloretone. This combination of adrenalin and chloretone has apparent j solved all previous difficulties lor in this we have a superior drug, one with not only valuable styptic properties, but also anesthetic and antiseptic qualities. Adrenalin clilo ride.solution c...

In further illustration of Langley's generalisation that the effect of adrenalin upon plain muscle is the same as the effect of exciting the sympathetic nerves supplying that particular tissue, it is found that the urethra of the cat is constricted alike by excitation of the hypogastric nerves and by the injection of adrenalin. The sacral visceral nerves, on the other hand, relax the urethra of...

The adrenochrome investigations into schizophrenia which I have pursued since 1952 and the recent important investigations into the relationship between heart function and (adrenalin —> adrenochrome) points to a connection between brain and cardiac disorder. I suggest there is a link between schizophrenia and some types of heart dysfunction. My hypothesis is that the biochemistry of schizophren...

The effects of glucagon, adrenalin or rapamycin on glycogen autophagy in the liver and heart of newborn rats were studied using biochemical determinations and electron microscopy. Glucagon or adrenalin increased autophagic activity in the hepatocytes and myocardiocytes, glycogen-hydrolyzing acid glucosidase activity in the liver and heart and degradation of glycogen inside the autophagic vacuol...

-TUNKENSTEIN, Greenblatt, and Solomon in 1948 reported on certain physiological changes which followed electroshock treatment. Since that time, several papers have appeared which have attempted to define the physiological meaning and the prognostic value of blood-pressure curves as they are affected by intravenous neo-epinephrine and intramuscular Mecholyl (methacholine). Funkenstein and his co...

Addition of adrenalin (10~moll~) to trout erythrocytes in an unbuffered saline resulted in a rapid acidification of the extracellular medium. This process was inhibited by amiloride (Ki/2~10~moll~) and by the removal of extracellular Na + . The rate of acidification was a saturable function of extracellular Na concentration. When extracellular pH was maintained constant by continual titration w...

In some earlier papers (I , 2, 3) on the production of peritoneal transudates in rabbits by the intravenous infusion of large quantities of sodium chloride solution or of mixtures of a sodium chloride and calcium chloride solution, or of these solutions with the addition of adrenalin, we found that both calcium chloride and adrenalin increased the amount of peritoneal transudate. We pointed out...