نتایج جستجو برای: adrenocortical adenoma
تعداد نتایج: 27212 فیلتر نتایج به سال:
PURPOSE We have reported previously nonsense inactivating mutations of the phosphodiesterase 11A (PDE11A) gene in patients with micronodular adrenocortical hyperplasia and Cushing syndrome. The aim of this study is to investigate the presence of somatic or germ-line PDE11A mutations in various types of adrenocortical tumors: ACTH-independent macronodular adrenocortical hyperplasia (AIMAH), adre...
We describe here a typical case of virilizing adrenocortical tumor. A 23-year-old Japanese woman had her male-like musculature, hirsutism, the absence of breast development and marked clitoromegaly. Adrenal androgens were remarkably elevated, with plasma dehydroepiandrosterone sulfate 2,752 micrograms/dl, plasma testosterone 250 ng/dl and urinary 17-ketosteroids 203.4 mg/day. A well-encapsulate...
OBJECTIVE This article aims to show the imaging characteristics of pediatric adrenocortical tumors. MATERIAL AND METHODS We review the imaging and histological findings in patients diagnosed with pediatric adrenocortical tumors at our tertiary hospital between 2000 and 2010. We analyze the findings at ultrasonography, computed tomography, and magnetic resonance imaging that can help orient th...
INTRODUCTION Adrenocortical carcinoma is a rare malignancy with a poor prognosis and presents with mass effects and less often with signs of hormone excess (approximately 60% of all adrenocortical carcinoma's). Hormonally active adrenocortical carcinomas most commonly secrete cortisol while the co-secretion of multiple steroid hormones is rare. CASE PRESENTATION We report the case of a 59 yea...
We present a machine learning system for the differential diagnosis of benign adrenocortical adenoma (ACA) vs. malignant adrenocortical carcinoma (ACC). The data employed for the classification are urinary excretion values of 32 steroid metabolites. We apply prototypebased classification techniques to discriminate the classes, in particular, we use modifications of Generalized Learning Vector Q...
Patients with Cushing's syndrome rarely become pregnant. This is a high risk situation both for the fetus and the mother, if untreated. We report a patient with Cushing's syndrome due to adrenocortical adenoma who became pregnant and was successfully treated with ketoconazole during the last period of pregnancy.
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