Human stress effects are cumulative. They are additive in nature. It affects all of us either directly or indirectly in day-today life. In this paper, stress effects are measured in terms of glucocorticoids(even though they are multivariate) particularly ACTH and Corticosterone. To find the long-term effect, the formula for finding the tail behaviour of the corresponding distributions with rand...

IN this paper we report observations on the treatment with ACTH of six female patients suffering from Sj6gren's syndrome. Each case was investigated on two occasions, an initial period of observation preceding the second admission for treatment. Five of the six patients underwent parotid biopsy, typical histological changes being seen in all. The methods used to assess improvement during therap...

Ectopic production of adrenocorticotropic hormone by carcinoid tumors is relatively uncommon and may not be recognized by physicians. This report describes a woman who had Cushing syndrome from the ectopic secretion of adrenocorticotropic hormone by a carcinoid tumor. Her cause of death was a pneumonia that may have been secondary to her untreated hypercortisolism. There are threeinstructive el...