Health benefit of garlic has been well established for a longtime during the history of mankind. Organosulfur compounds of garlic including δ-glutamyl-S-allyl-L-cysteins and S-allyl-Lcysteine (SAC) sulfoxides are known as major components of bioactivity; however, raw garlic is easy to be converted into bio-inactive form. Thus, many types of garlic extract or preparation with diverse composition...

OBJECTIVES Previous studies demonstrated that aged garlic extract reduces multiple cardiovascular risk factors. This study was designed to assess whether aged garlic extract therapy with supplements (AGE+S) favorably affects inflammatory and oxidation biomarkers, vascular function and progression of atherosclerosis as compared to placebo. METHODS In this placebo-controlled, double-blind, rand...

The present study has been carried out to investigate the effect of aqueous extract of shallot (Allium ascalonicum) and garlic (Allium satium) on the fasting insulin resistance index (FIRI) and intraperitoneal glucose tolerance test (IPGTT) of fructose-induced insulin resistance rats. Male albino Wistar rats were fed either normal or high-fructose diet for a period of eight weeks. Fasting blood...

BACKGROUND/OBJECTIVES Irisin, a newly identified hormone, is associated with energy homeostasis. We investigated whether aged garlic extract (AGE) and exercise training intervention could improve body weight, insulin sensitivity, skeletal muscle fibronectin domain containing protein 5 (FNDC-5) levels, and plasma irisin in high-fat diet (HFD). MATERIALS/METHODS Male Sprague Dawley rats were fe...

In Ethiopia, honey produced by T. iridipennis in combination with garlic is widely used for traditional treatment of different infections. The objective of this study was to evaluate the synergic antibacterial effect of T. iridipennis honey and garlic mixture against standard and clinical pathogenic bacteria. The antimicrobial activity of garlic extract, tenegn honey and mixture of tenegn honey...

Recent evidence from studies suggests that aged black garlic also has an effect on health. The major aim of the present study is to compare the effect of raw and aged black garlic on postischemic cardiac recovery. Male Sprague Dawley rats were randomly divided into three groups. Animals of the first group were fed with raw garlic, animals of the second group received aged black garlic, while th...

OBJECTIVE Garlic is a plant has been used as a flavor, and anti-microbial and anti-diarrheal agent. Infectious bronchitis virus (IBV) is a coronavirus. The available vaccines against IBV cannot cover new variants. This study evaluated the inhibitory effects of garlic extract on IBV. MATERIALS AND METHODS The constituents of garlic extract were detected by gas chromatography. This study was do...