Alcohol abuse is a common human disorder with high rate of comorbidity with other psychiatric disorders. To identify candidate mechanisms for alcohol abuse, the expression of 12,626 genes was measured in postmortem temporal cortex from 11 subjects with a history of alcohol abuse or dependence, with or without other psychiatric diagnoses and compared pairwise with the expression in 11 nonalcohol...

The harmful use of alcohol inflicts great deal of social and economic losses on individuals and societies. Given the increase in world population and the predicted increase in alcohol consumption, the alcohol related burden of disease progressively catches higher ranks in the list of factors threatening humans' life. It has been considered that the social and economic burden related to alcohol ...

The purpose of this study was to investigate the differences in short-term course between DSM-IV alcohol abuse and alcohol dependence in a community sample of men and women. Eight hundred seventy-six individuals were given a baseline interview that included DSM-IV criteria for alcohol use disorders, and were followed up with a similar interview approximately one year later. Group differences we...

Alexithymia and avoidance coping strategies are both associated with alcohol abuse, but their effects have been seldom studied simultaneously. The present study investigated the interplay between alexithymia and avoidance coping strategies in predicting the severity of alcohol abuse in an alcohol-dependent sample. The TAS-20 and COPE-NVI questionnaires were administered to 110 alcoholic inpatie...

background: attention deficit hyperactivity disorder (adhd) is a common psychiatric disorder among children and adolescents that can be continued into adulthood in 30 to 50% of cases. adult adhd disorder can affect the performance of an individual and may predispose to drug abuse, alcoholism, smoking, sexual offenses, violation of law, educational and other social problems. the coincidences of ...

OBJECTIVE To determine the status of adverse childhood experiences (ACEs) and the association of multiple ACEs with both parental alcoholism and later personal alcohol abuse among Chinese medical students with a view of improving adolescent health and reducing alcohol abuse among them. METHODS In this cross-sectional study, 2073 Chinese medical students completed a survey on ten categories of...

Alcohol abuse is a global problem due to the financial burden on society and the healthcare system. While the harmful health effects of chronic alcohol abuse are well established, more recent data suggest that acute alcohol consumption also affects human wellbeing. Thus, there is a need for research models in order to fully understand the effect of acute alcohol abuse on different body systems ...

Childhood emotional abuse has been linked to problematic alcohol use in later life but there is a paucity of empirically based knowledge about the developmental pathways linking emotional abuse and alcohol use in young adulthood. Using a community sample of young individuals aged 18-25 (N=268; female 52%), we performed structural equation modeling to investigate whether emotional abuse influenc...

The scope of this study is to estimate the prevalence of alcohol abuse and alcohol addiction and the respective associated factors in the urban population of a city of northeastern Brazil. It is a population-based cross-sectional study that investigated the consumption of alcohol of 270 people living in the urban area of Jequié, State of Bahia. Alcohol abuse, defined by a score of > 8 from resp...

The purpose of the study was to estimate the risk of substance use disorder (SUD) and alcohol abuse in adulthood among children and adolescents with attention-deficit hyperactivity disorder (ADHD) compared to the background population. Furthermore, to examine whether the age at initiation and duration of stimulant treatment in childhood predicts SUD and alcohol abuse in adulthood. 208 youths wi...