Hybridization of murine myeloma cells P3-X63-Ag8.653 with splenocytes from a BALB/c mouse immunized with the syngeneic anti HLA-DR1,4,w6,w8,w9 MAb AC1.59 resulted in the development of 108 hybridomas secreting antiidiotypic antibodies. 100 of them inhibited the binding of MAb AC1.59 to target cells. Detailed analysis of the antiidiotypic MAb F5-444, F5-830, F5-963, F5-1126, F5-1336, and F5-1419...

We report engineering Neurospora crassa to improve the yield of cellobiose and cellobionate from cellulose. A previously engineered strain of N. crassa (F5) with six of seven β-glucosidase (bgl) genes knocked out was shown to produce cellobiose and cellobionate directly from cellulose without the addition of exogenous cellulases. In this study, the F5 strain was further modified to improve the ...

Template matching is a widely used technique in many of image processing and machine vision applications. In this paper we propose a new as well as a fast and reliable template matching algorithm which is invariant to Rotation, Scale, Translation and Brightness (RSTB) changes. For this purpose, we adopt the idea of ring projection transform (RPT) of image. In the proposed algorithm, two novel s...

BACKGROUND Factor V deficiency is a rare autosomal recessive hemorrhagic disorder, associated with bleeding manifestations of variable severity. In the present study, we investigated the molecular basis of factor V deficiency in three patients, and performed a comprehensive analysis of the factor V gene (F5) splicing pattern. DESIGN AND METHODS Mutational screening was performed by DNA sequen...

  Fuzzy time series have been developed during the last decade to improve the forecast accuracy. Many algorithms have been applied in this approach of forecasting such as high order time invariant fuzzy time series. In this paper, we present a hybrid algorithm to deal with the forecasting problem based on time variant fuzzy time series and particle swarm optimization algorithm, as a highly effi...

ion and judgment (R5 0.049, F5 5.39, P5.005) Education 0.05 0.02 2.05 0.14 .04 Systolic blood pressure 0.01 0.01 2.68 0.18 .008 Language (R5 0.116, F5 27.50, Po.001) Education 0.09 0.02 5.24 0.34 o.001 Drawing (R5 0.103, F5 11.91, Po.001) Education 0.11 0.03 3.59 0.24 o.001 eGFR 0.03 0.01 3.32 0.22 .001 List-generating fluency (R5 0.023, F5 5.24, P5.02) eGFR 0.02 0.01 2.29 0.16 .02 Body mass in...

Objective: Intracellular signaling of activin and transforming growth factor-b (TGF-b) is thought to be mediated by the same molecules (Smad2/3 and Smad4). Although differentiation of murine erythroleukemia F5-5.fl cells is induced by activin, it is not induced by TGF-b, suggesting that at some point TGF-b signaling is defective. The aim of this study was to investigate the unresponsiveness of ...