Periodontium is a complex organ composed of mineralized epithelial and connective tissue. Dexamethasone could stimulate proliferation of osteoblast and fibroblasts. This study aimed to assess the osteogenic effect of dexamethasone on periodental ligament (PDL) stem cells. PDL stem cells were collected from periodontal ligament tissue of root of extracted premolar of young and healthy people. Th...

A decrease in the lineage commitment of multipotent Mesenchymal stem cells (MSC) to the bone forming osteoblast lineage and an increase in the commitment to the fat forming adipocyte lineage is more common in bone marrow of elderly persons. A link between methylation status and MSC differentiation remains unclear. Therefore, we hypothesize that hypomethylation may decide the fate decisions of M...

BACKGROUND This cross-sectional population-based study was conducted to elucidate the prevalence of vitamin D deficiency, bone turnover marker's variation and its influencing factors among adolescents of Tehran. METHODS Totally 444 middle and high school (53.6 % in high school) students (both girls and boys) were recruited. A short food frequency questionnaire designed to estimate dietary cal...

Human milk is the main source of nutrients for a child during the first months of life. Alkaline phosphatase (EC 3.1.3.1) is a very important enzyme in clinical chemistry because of its activity in various tissues and biological fluids, being an indicator of physiological or diseased states. Milk contains several phosphatases, the principal ones being alkaline and acid phosphomonoesterases whic...

The W.L.H. chicks carrying A. galli infectioin showed ascridiasis and anemia. The biochemical responses such as glucose, protein, cholesterol, urea, acid phosphates and alkaline phosphatase level after 16 days and 32 days at low dose and high dose of infection were studied. The infection showed a significant increase in serum cholesterol and serum urea levels in all the experimental cases. The ...

1. The stability of the tetrameric form of Escherichia coli alkaline phosphatase was examined by analytical ultracentrifugation. 2. The stopped-flow technique was used to study the hydrolysis of nitrophenyl phosphates by the alkaline phosphatase tetramer at pH7.5 and 8.3. In both cases transient product formation was observed before the steady state was attained. Both transients consisted of th...

The phoD gene encoding the membrane-bound alkaline phosphatase (ALPI) from Zymomonas mobilis CP4 was cloned and sequenced. Both the translated sequence and the properties of the recombinant enzyme were unusual. Z. mobilis ALPI was monomeric (M(r) 62,926) and hydrolysed nucleotides more effectively than sugar phosphates. The translated sequence contained a single hydrophobic segment near the N-t...

A study was conducted to evaluate the electrolyte imbalances in infantile seizures. Materials and Methods: Thirty-six infants admitted at the Malabar Institute of Medical sciences Calicut formed the test group. The values are compared with that of 20 apparently healthy infants admitted for other illness. Serum ionized calcium and total calcium, sodium, potassium, Magnesium, inorganic phosphorus...