Bio-Oss (BO), composed of anorganic bovine bone, is widely used in several bone regeneration procedures in oral surgery. PerioGlas (PG) is an alloplastic material that has been used for grafting of periodontal osseous defects since the 1990s. However, how these biomaterials alter osteoblast activity to promote bone formation is poorly understood. We attempted to address this question by using m...

Important functional and esthetical impairments appear due to bone defects of the craniofacial skeleton. The development of rapid-prototyping technologies offers the possibility of reconstructing some of the bone defects with custom-made craniofacial implants from alloplastic materials. Bone defects of the skull were rehabilitated using custom-made implants of polymethylmethacrilate. The implan...

This research was developed in order to demonstrate the tissue engineering method as an alternative to conventional methods for bone reconstruction, in order to overcome the frequent failures of alloplastic commercial biomaterials, allografts and autografts. Tissue engineering is an in vitro method used to obtain cell based osteoinductive bone grafts. This study evaluated the feasibility of cre...

381 including infection and allergic reaction, and its use should definitely be avoided in the case of children, whose bones have not yet stopped growing. In the case of the sixteen-year-old patient in this study, while alloplastic cranioplasty was possible, as the growth of the skull bone was nearly complete, the patient and his guardian decided upon autologous cranioplasty. In cases of large ...

Objectives: Highlight the outcome of alveolar grafting with synthetic bone substitute (Osteon III) only in various defect volumes. Material and Method: Prospective study accomplished on 55 patients (6-13 years aged) unilateral cleft. Osteon III, consisting hydroxyapatite (HA) tricalcium phosphate (TCP) used to reconstruct defect. Alveolus diameter calculated before surgery (V1), after 3 months ...

Porous polyethylene (PP or Medpor®) is an alloplastic material used worldwide for craniofacial reconstruction. Although several clinical studies are available, how this material alters osteoblast activity to promote bone formation is poorly understood. To study how PP can induce osteoblast differentiation in mesenchymal stem cells, the expression levels of bone related genes and mesenchymal ste...

Osseointegration can be defined as a direct structural and functional link between bone implant surface. Asymptomatic rigid fixation of the alloplastic material in is crucial for stability long-term success dental treatment. The connection surrounding tissue extremely dynamic. This interaction basis formation new structure—the implant-tissue interface. process osseointegration combination biolo...

Gingival recessions constitute serious limitations for effective interdisciplinary periodontal, orthodontic, and implant therapy. A proper bone morphology of the alveolar soft tissues that cover it are interdependent. The regeneration procedures known to date based on use autogenous bone, or its allogeneic, xenogeneic, alloplastic substitutes. These substitutes characterized by different osteog...

The use of alloplastic materials in ossicular reconstruction has a long history. However, many new materials have been described and become commercially available without any evidence that they are superior to the existing ones. The aim of the present literature review is to understand why changes in materials used for ossicular reconstruction have occurred. The literature review was conducted ...