BACKGROUND: Aloe vera, a succulent plant prevalent in hot, dry regions of Asia, Africa, and other areas, has been used in traditional medicine for many centuries. It is easily propagated in most places where the climate is hot and dry. The gel and dried latex obtained from aloe leaves are used for relief of constipation; for wound healing; and for treatment of burns, psoriasis, frostbite, ulcer...

Endochondral bone formation is the process by which mesenchymal cells condense into chondrocytes, which are ultimately responsible for new bone formation. The processes of chondrogenic differentiation and hypertrophy are critical for bone formation and are therefore highly regulated. The present study was designed to investigate the effect of aloe-emodin on chondrogenic differentiation in clona...

Aloe vera is used worldwide for several medical purposes as alternative medicine. The present study was aimed to evaluate the antidiabetic, antihyperlipidemic and antioxidative activity of aloe vera gel extract in diabetic and control rats. Forty male albino rats, weighing (95±5g) were divided into four groups; group 1: normal control, group 2: Diabetic control group (by Intraperitoneal injecti...

OBJECTIVE Aloe vera is an herbal medicine, which has wound healing effects in burn injury. This study assessed the effects of Aloe vera cream in reducing postoperative pain, postdefection pain, and its promotion of wound healing after open hemorrhoidectomy. DESIGN A prospective, randomized, double-blind, placebo-controlled trial was conducted comparing the effects of a cream containing Aloe v...

Aloe vera, a common ingredient in cosmetics, is increasingly being consumed as a beverage supplement. Although consumer interest in aloe likely stems from its association with several health benefits, a concern has also been raised by a National Toxicology Program Report that a nondecolorized whole leaf aloe vera extract taken internally by rats was associated with intestinal mucosal hyperplasi...

Barbados aloe (Aloe vera (L.) Burm. F.) has traditionally been used for healing in natural medicine. However, aloe is now attracting great interest in the global market due to its bioactive chemicals which are extracted from the leaves and used in industrial preparations for pharmaceutical, cosmetic, and food products. Aloe originated from tropical and sub-tropical Africa, but it is also now cu...

The anthraquinones emodin and aloe-emodin are abundant in rhubarb. Several lines of evidence indicate that emodin and aloe-emodin have estrogenic activity as phytoestrogens. However, their effects on estrogen receptor α (ER α ) activation and breast cancer cell growth remain controversial. The goal of this study is to investigate the effects and molecular mechanisms of emodin and aloe-emodin on...

Amongst the numerous species of Aloe used in traditional medicine, A. vera stands on its own as the basis of an enormous global industry (Figures 1 & 2), with an estimated annual retail value exceeding 110 billion US dollars (International Aloe Science Council 2004). In South Africa, A. ferox has become an important commercial medicinal plant, not only for its traditional use as laxative bitter...

Background: Stress has different effects on the body and endocrine system. Objectives: The main aim of this study is to determine the effects of immobilization stress and Aloe vera extract on levels of TSH, T3 or T4 in male rats. Materials and Methods: In this experimental study, 90 male Wistar rats were randomly divided into 9 groups of control, receiving normal saline, receiving Aloe vera ext...

Aims: To screen for phytochemicals present in Aloe barbadensismiller (Aloe vera) growing within the Main Campus of Nasarawa State University Keffi (NSUK), determine biofilm forming ability, and to investigate antibiofilm activity plant extracts on formed by clinical isolates Candida isolated from urinary catheters.
 Study Design: The leaf vera were collected maceration method was used extr...