BACKGROUND Semen armeniacae amarum (SAA) is a Chinese traditional medicine and has long been used to control acute lower respiratory tract infection and asthma, as a result of its expectorant and antiasthmatic activities. However, its mutagenicity in vitro and in vivo has not yet been reported. The Ames test for mutagenicity is used worldwide. The histidine contained in biological samples can i...

USDA-ARS Corn Insects and Crop Genetics Research Unit, Ames, IA 50011, Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USDA-ARS Plant Genetics Research Unit and Division of Plant Sciences, University of Missouri, Columbia, MO 65211, USDA-ARS Plant Gene Expression Center, Albany, CA 94710, Department of Molecular and Cell Biology, University of Califo...

W. Jayasekara, Y. Lee, 2 Abhishek Pandey, 2 G. S. Tucker, 2 A. Sapkota, 2 J. Lamsal, 2 S. Calder, D. L. Abernathy, J. L. Niedziela, B. N. Harmon, 2 A. Kreyssig, 2 D. Vaknin, 2 D. C. Johnston, 2 A. I. Goldman, 2 and R. J. McQueeney 2 Ames Laboratory, Ames, Iowa, 50011, USA Department of Physics and Astronomy, Iowa State University, Ames, Iowa, 50011, USA Oak Ridge National Laboratory, Oak Ridge,...

Jiangfeng Zhou, Eleftherios N. Economon, Thomas Koschny, 4 and Costas M. Soukoulis 4 Department of Electrical and Computer Engineering and Microelectronics Research Center,Iowa State University, Ames, Iowa 50011 Institute of Electronic Structure and Laser FORTH, and Department of Physics, University of Crete, Greece Ames Laboratory and Department of Physics and Astronomy,Iowa State University, ...

Composite Response Surface Designs for Factors With Jointly Symmetric Effects Max D. Morris, Brad Dilts, Stuart J. Birrell & Philip M. Dixon a Department of Statistics and Department of Industrial and Manufacturing Systems Engineering, Iowa State University, Ames, IA 50011 b CNH America, LLC, 3301 S. Hoover Road, Wichita, KS 67277 c Department of Agricultural and Biosystems Engineering, Iowa St...

mebudipine is a new dihydropyridine calcium channel blocker, synthesized in our laboratory, for treatment of hypertension. it has shown a better efficacy than other drugs in this group. for assessing the risks of this drug, certain safety tests in the preclinical stage have been performed. in this study mutagenic effect of mebudipine was evaluated using ames assay that could assess the mutageni...

Analyte Control I Control II Control I Control II Sodium 0.9(117.7) 1.2(142.7) 1.1(118.7) 1.2(142.0) Potassium 1.1(4.18) 1.3(6.1) 1.1(4.23) 0.9(6.60) Glucose 1.8(6.29) 2.1(14.87) 1.4(4.98) 0.9(14.51) Amylase 4.7(38.1) 6.1(113) 4.5(36.6) 3.9(121.3) Creatinine 19.4(70.4) 5.4(478.9) 24.9(63.2) 3.5(453.3) Bilirubin 3.4(22.2) 1.1(87.9) 4.1(22.3) 1.3(87.3) Urate 1.4(270.9) 1.4(512.7) 0.9(262.9) 0.9(4...

In this paper, we describe the experiences of the Automated Software Engineering Group at the NASA Ames Research Center in the development and application of three di erent transformation systems. The systems span the entire technology range, from deductive synthesis, to logic-based transformation, to almost compiler-like source-to-source transformation. These systems also span a range of NASA ...

Mebudipine is a new dihydropyridine calcium channel blocker, synthesized in our laboratory, for treatment of hypertension. It has shown a better efficacy than other drugs in this group. For assessing the risks of this drug, certain safety tests in the preclinical stage have been performed. In this study mutagenic effect of mebudipine was evaluated using Ames assay that could assess the mutageni...

Mebudipine is a new dihydropyridine calcium channel blocker, synthesized in our laboratory, for treatment of hypertension. It has shown a better efficacy than other drugs in this group. For assessing the risks of this drug, certain safety tests in the preclinical stage have been performed. In this study mutagenic effect of mebudipine was evaluated using Ames assay that could assess the mutageni...