Considering many applications of functionalized metal oxide nanoparticles in magnetic resonance imaging, drug delivery, neutron irradiation, electronics, catalysis and optics; herein, a new strategy is developed to functionalize magnetite nanoparticles to improve their performances in the delivery of acyclovir. In this study, magnetite Fe3O4 nanoparticles are synthesized b...

The synthesis of functionalized 2-oxo-2H-coumarin derivatives has been studied by a one-pot reaction of o-hydroxybenzaldehyde, ethyl 2-bromoacetate and triphenylphosphine in the presence of catalytic amount of triethyl amine in EtOAc, water or under solvent free conditions. We have found the best results obtained under solvent free condition.

At many portals of entry the relative uptake by phagocytes and non-phagocytic cells has a prominent effect on availability and biological action of nanoparticles (NPs). Cellular uptake can be determined for fluorescence-labeled NPs. The present study compares three methods (plate reader, flow cytometry and image analysis) in order to investigate the influence of particle size and functionalizat...

Small-molecule microarrays composed of tens of thousands of distinct synthetic molecules, natural products, and their combinations/modifications provide a high-throughput platform for studying protein-ligand interactions. Immobilization of small molecule compounds on solid supports remains a challenge as widely varied small molecules generally lack unique chemical groups that readily react with...

A new family of duplex-forming recognition encoded oligomers, capable sequence selective duplex formation and template directed synthesis, was developed. Monomers equipped with both amine aldehyde groups were functionalized...

Contamination of water from nanomaterials will be an emerging problem in the future due to incorporation of nanomaterials in many commercial products and improper disposal of waste materials. In this report, electrospun polyvinyl alcohol nanofibers (PVA NFs) with diameters ranging between 300 and 500 nm were used for the extraction of nanosized contaminants from the aqueous environment. To obta...

Pure polyamide 6 (PA6) and polyamide 6/carbon nanotube (PA6/CNT) composite samples with 0.5 weight percent loading of pristine or functionalized CNTs were made using a solution mixing technique. Modification of nanotube surface as a result of chemical functionalization was confirmed through the presence of lattice defects as examined under high-resolution transmission electron microscope and ab...

The first highly enantioselective α-fluorination of ketones using organocatalysis has been accomplished. The long-standing problem of enantioselective ketone α-fluorination via enamine activation has been overcome via high-throughput evaluation of a new library of amine catalysts. The optimal system, a primary amine functionalized Cinchona alkaloid, allows the direct and asymmetric α-fluorinati...

Functionalized phenols based on tyramine were synthesized in order to be selectively grafted on to hexachlorocyclotriphosphazene, affording a variety of functionalized dendrons of type AB(5). The B functions comprised fluorescent groups (dansyl) or dyes (dabsyl), whereas the A function was provided by either an aldehyde or an amine. The characterization of these dendrons is reported. An unexpec...

The incorporation of Pt nanoparticles into a highly stable and porous amine-functionalized MIL-101(Cr) was performed for construction of a visible light driven H2 evolution system with high activity and strong stability.