gamma aminobutyrate (gaba) is a non-protein amino acid that is thought to play an important role in the modulation of the central response to stress. mechanisms by which gaba may facilitate these responses to stress are metabolic and/or mechanical disruptions. environmental stresses increase gaba accumulation through cytosolic acidification, induce an acidic ph-dependent activation of glutamate...

This study was carried out to determine the effects of γ-aminobutyric acid on the reproductive performance, antioxidative status and biochemical indices of lactating sows. Forty-two lactating sows (Landrace×Large White) were blocked by body weight, parity and backfat and randomly assigned to 6 treatments: 0 (control), 100, 200, 300, 400 and 500 mg γ-aminobutyric acid /kg diet. The average tempe...

although many studies have highlighted the role of gamma-aminobutyric acid (gaba) in the pathophysiology of psychosis, there is no drug-induced animal model in which gaba is manipulated. in this article we propose a hypothetical animal model for psychosis based on the silencing gabaergic system.  the presentation also suggest pre-pulse inhibition test as a preferred approach towards proving thi...

BACKGROUND Gamma-aminobutyric acid-B receptor autoantibodies are becoming an increasingly recognized contributor to the spectrum of autoimmune limbic encephalitis. They are classically associated with seizures and behavioral disturbance, and may coexist with other autoantibodies. Many are paraneoplastic, most commonly associated with small cell lung cancer. Until now there have been no reports ...

In continuation of previous studies, the intraarterial fusion of L-glutamic acid for 24 hr was found to oppose the decrease in acetylcholinesterase and butyrylcholinesterase in the superior cervical ganglion of the cat that otherwise occurs 48 hr after preganglionic denervation. The combination of glutamic acid and gamma-aminobutyric acid, in concentrations that were inactive individually, like...