BACKGROUND Overexpression of Met tyrosine kinase receptor is associated with poor prognosis. Overexpression, and particularly MET amplification, are predictive of response to Met-specific therapy in preclinical models. Immunohistochemistry (IHC) of formalin-fixed paraffin-embedded (FFPE) tissues is currently used to select for 'high Met' expressing tumors for Met inhibitor trials. IHC suffers f...

conclusions based on the findings obtained, the rate of total waste generation in the amol hospital is similar in range to that of other iranian hospitals, however, the hazardous fraction of this waste was high in comparison to other previous studies, and this is probably due to improper separation and management of the waste materials. results based on this study’s findings the average rate of...

introduction: due to irregular growth and expansion of cities, especially in developing countries, various issues and difficulties have arisen in different economic, social and ecological fields and various measurements and approaches in order to supply desirable conditions for today and future generations. healthy city approach is one these approaches as today it’s a new mechanism proposed by ...

Steroid sulfatase (STS) hydrolyzes several sulfated steroids such as estrone sulfate, dehydroepiandrosterone sulfate, and cholesterol sulfate. In the present study, we have measured STS mRNA levels in 97 breast cancers by reverse transcription-PCR using a fluorescent primer in the presence of an internal standard RNA and evaluated its association with disease-free and overall survival. The medi...

INTRODUCTION Current methods to determine HER2 (human epidermal growth factor receptor 2) status are affected by reproducibility issues and do not reliably predict benefit from anti-HER2 therapy. Quantitative measurement of HER2 may more accurately identify breast cancer (BC) patients who will respond to anti-HER2 treatments. METHODS Using selected reaction monitoring mass spectrometry (SRM-M...

If n is a nonnegative integer, then denote by ∂H the space of all complex valued functions f defined on D such that f, f , f , . . . , f (n) belong to H∞, with the norm

Steroid sulfatase (STS) hydrolyzes several sulfated steroids such as estrone sulfate, dehydroepiandrosterone sulfate, and cholesterol sulfate. In the present study, we have measured STS mRNA levels in 97 breast cancers by reverse transcription-PCR using a fluorescent primer in the presence of an internal standard RNA and evaluated its association with disease-free and overall survival. The medi...

Data on the chromosome analysis of leukemic cells from consecutive patients with nonlymphocytic leukemia from six independent laboratories in the United States. Europe. and Australia were combined. The karyotypic pattern determined with banding was correlated with the patient’s age and the morphological type of leukemia according to the FAB classification. Of the 503 patients in the combined st...