We describe a computation that determined the number of knight's tours of a standard chessboard. We also verify Knuth's count of tours with a symmetry.

We read with great interest the Highlight Review by Dr C GruÈ ndker entitled `Cytotoxic luteinizing hormonereleasing hormone conjugates and their use in gynecological cancer therapy' in the European Journal of Endocrinology (1). This excellent article provides a detailed description of recent developments in the field of targeted chemotherapy based on luteinizing hormone-releasing hormone (LH-R...

Recently, we developed a series of cytotoxic peptide conjugates containing 14-O-glutaryl esters of doxorubicin (DOX) or 2-pyrrolino-DOX (AN-201). Serum carboxylesterase enzymes (CE) can partially hydrolyze these conjugates in the circulation, releasing the cytotoxic radical, before the targeting is complete. CE activity in serum of nude mice is about 10 times higher than in human serum. Thus, w...

purpose: to evaluate the 8-year results of excimer laser photorefractive keratectomy (prk) for myopia in terms of safety, stability and late complications. methods: of 203 myopic patients who underwent prk with single-step method using nidek ec-5000 excimer laser with 5-6 mm ablation zones at basir eye center, tehran-iran from 1996 to 1998, 179 eyes of 98 patients who completed 8 years of follo...