Background: Morphine and lidocaine are known to influence the perception of pain. The present study sought to determine the influence of local administration of morphine on lidocaine-induced analgesia in morphine non-dependent (MND), morphine dependent (MD) and morphine withdrawal (MW) animals. Methods: Adult male Wistar rats were divided into four groups: Control, MND, MD and MW rats. Lidocai...

Neuraxial analgesia is widely accepted as the most effective and the least depressant method of providing pain relief in labor. Over the last several decades neuraxial labor analgesia techniques and medications have progressed to the point now where they provide high quality pain relief with minimal side effects to both the mother and the fetus while maximizing the maternal autonomy possible fo...

CONTEXT AND OBJECTIVE Post-thoracotomy pain is a severe and intense pain caused by trauma to ribs, muscles and peripheral nerves. The current study aimed to compare subpleural analgesia (SPA) with thoracic epidural analgesia (TEA) in patients undergoing thoracotomy. DESIGN AND SETTING Randomized study at Ankara Numune Education and Research Hospital, in Turkey. METHODS Thirty patients prese...

conclusions it seems that, in patients undergoing pncl, sa is as effective and safe as ga. patients who undergo pncl under sa require smaller amounts of analgesic dose and show hemodynamic stability during surgery and recovery time. also, sa technique provides decreased blood loss and shortened surgery as well as anesthesia times compared to ga. results map and heart rate show no significant di...

conclusions the results of this study showed that lidocaine spray had the best pain controlling effect at 20 minutes in the recovery room, but after 40 minutes, ketamine and morphine sprays were more effective than the lidocaine spray. results in the early postoperative period (time: 0) and at 20, 40 and 60 minutes of recovery time, flacc scale scores in the control group were higher than in th...

in a randomized, double blind study , we compared post operative pain and analgesic requirement in patients undergoing cesarean section with two types of general anesthesia: standardized general anesthesia (control group=26 cases) and preemptive low-dose ketamine (0.2 mg/kg) administered prior to anesthesia induction (keratmine group=27 cases). postoperative analgesia was provided for both grou...

background: pain in infancy is a developmental process. due to the underdeveloped pain pathways in the spinal cord, the threshold of stimulation and sensation of pain is low at birth and has potential impacts on increasing the central effects of pain. primary trauma during infancy can cause long term changes in structure and function of pain pathways that continue until adulthood. lack of pain ...

background and objectives: previous studies have shown the antinociceptive effect of morphine in animal models, but the specific anti-pain consequence of the abuse drug in female animals is unclear. the present research showed the morphine antinociception in female wistar rats using formalin test. materials and methods: subjects were 40 female wistar rats purchased from pasteur institute of ira...

transcutaneous electrical nerve stimulation (tens) is an analgesia inducing method with increasing applications in clinical procedures. in this study we tried to evaluate the role of the adrenergic system and its different adrenoceptor subtypes in tens-induced analgesia. two types of low and high frequency electrical stimuli were used in rats through needle electrodes, inserted at the base of t...