Plasma sex hormone binding globulin (SHBG) and testosterone levels were measured in 29 patients with epilepsy (16 men and 13 women), most of them on chronic therapy with anticonvulsant drugs. Sex hormone binding globulin concentrations were increased in both sexes and testosterone levels in male patients. It is postulated that anticonvulsants may induce hepatic synthesis of SHBG.

Recent studies have suggested that vitamin D3 may have an immunoregulatory role in vitro. The vitamin D3 metabolism in 35 patients with primary Sjögren's syndrome was investigated by measuring blood concentrations of 1 alpha,25-dihydroxyvitamin D3 (1 alpha,25-(OH)2D3) and 25-hydroxyvitamin D3 (25-OHD3), as well as phenotypes and blood concentrations of Gc globulin, the main vitamin D3 binding p...

1. The possible mechanism of the oestrogenic inhibition of the androgen-dependent synthesis of alpha2u-globulin in rat liver was explored by a correlative study of the amounts of alpha2u-globulin, its corresponding mRNA and circulating testosterone in oestrogen-treated male rats. 2. Daily treatments of mature male rats with oestradiol-17beta (10 microgram/100g body wt.) decreased and ultimately...

pesticides are one of the most pollutants in aquatic ecosystems. monitoring of aquatic pollution with these compounds is very important. therefore, health status of aquatic animals can be used as a bio-indicator for pollution monitoring in surface waters. diazinon is an organophosphorous pesticide, which is found in the aquatic environment of iran. the concern has arisen over the ability of thi...

This experiment was conducted to determine the blood chemistry and carcass characteristics of broilers fed malted sorghum sprouts (MSP) or wheat offal (W/O)-based diets supplemented with yeast culture enzyme. A total two hundred forty 28-day old, Marshal Broiler chickens used for were randomly allotted 8 dietary treatment groups 30 birds each. Each group replicated thrice 10 per replicate. Data...

Abstract Establishing any characteristic associations between the serum parameters of thyroid function and proteins in pregnancy may aid elucidating role gland regulation pregnancy-specific metabolic processes selecting candidate biomarkers for use their clinical assessment. Concentrations stimulating hormone (TSH), free tri-iodothyronine (fT3) thyroxine (fT4), six electrophoretically separated...

1. The concentrations of total nitrogen, hexosamine and protein-bound hexose and the amounts of these constituents precipitated by trichloroacetic acid were determined in the serum of pigs at various ages from 57 days after copulation to 42 days after birth. The concentrations of the same constituents were also determined in the serum of mature pigs. 2. A rise in the concentrations of total nit...

In an earlier communication (1) attention was called to the marked depressions of albumin: globulin ratios that frequently occur in the course of louse-borne typhus fever. Serum globulin concentrations in a number of cases were found to be higher than 5 grams per 100 ml. Because of the consistent rise in serum globulins in this disease, possibly a feature of the immune response, it was of inter...

BACKGROUND AND OBJECTIVES An abnormal anion gap and an increased total protein and globulin are clues to the diagnosis of monoclonal gammopathy. We explored the utility of these markers in IgG, IgA, IgM, and free light chain monoclonal gammopathies. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The anion gap, Na(+) - (Cl(-) + HCO(3)(-)), corrected for hypoalbuminemia, was calculated in patien...