BACKGROUND The degree of androgenetic alopecia is generally evaluated either by global clinical scales or time-consuming methods like phototrichogram or histological studies. We describe a new clinical and reliable scoring method based on hair diameter diversity. OBSERVATIONS (1) The clinical macroscopic scoring we propose for hair density was significantly correlated with Hamilton classifica...

INTRODUCTION Androgenetic alopecia (AGA) is the most common form of hair loss. Clinically observed hair loss is due to the continuous miniaturization of affected hair follicles. Genetic factors and androgenic factors especially dihydrotestosterone (DHT), which is a testosterone tissue metabolite, play major roles in the pathogenesis of AGA. However, expert opinions about the usefulness of DHT i...

Androgenic alopecia (AGA), scalp hair loss, occurs due to the hyperactivity of steroid 5α-reductase2 (SRD5A2), which metabolizes testosterone into 5α-dihydroxytestosterone. Finasteride, an FDA-approved drug producing many side effects, is a commonly used competitive inhibitor for SRD5A2 treat AGA. As number mushroom species have been patients having loss problems since ancient times, in present...

Androgenetic alopecia is considered to be associated with coronary heart disease but the explanation of this association remains unknown. Hypertension is highly prevalent in patients with coronary heart disease. Essential hypertension is linked to hyperaldosteronism and spironolactone, an antihypertensive drug which is a mineralocorticoid receptor antagonist, has been used for a long time in th...

Background and Purpose: Androgenic alopecia (AGA) is one of the common presenting problems in dermatology. Relationship between AGA and atherosclerosis/cardiovascular disorders has been surveyed in many studies with different results: some approved it and the others did not. The aim of this study was comparative survey of carotid intima – media thickness between cases with AGA and controls. Sub...

OBJECTIVE To describe an organized diagnostic approach for both nonscarring and scarring alopecias to help family physicians establish an accurate in-office diagnosis. To explain when ancillary laboratory workup is necessary to confirm the diagnosis. QUALITY OF EVIDENCE Current diagnostic and therapeutic interventions for hair loss are based on randomized controlled studies, uncontrolled stud...

This study conducted a systematic review of studies on the relationship between androgenic alopecia and metabolic syndrome. We performed comprehensive databases including PubMed, Web Knowledge, Google Scholar, Scopus, Embase, extracted relevant articles published from 2010 to 2018. The case reports, articles, or lacking full-text were excluded. examined nine for meta-analysis step. results show...