Isolation of autochthonous bacteria from marine sources as a potential probiont in biocontroling against pathogenic Vibrio species in the shrimp culture industry was the aim of current research. A total of 198 bacterial strains were isolated from pond water, sediment, hepatopancreas and gut samples of shrimps after culturing the samples on Tryptic Soy Agar and incubated at 30 °C for 24-48 h. Th...

LBVS of 12480 in-house compounds, followed by HTRF assay, resulted in one nonsteroidal compound (11) with antagonistic activity against FXR (69.01 ± 11.75 μM). On the basis of 11, 26 new derivatives (12a-z) were designed and synthesized accordingly. Five derivatives (12f-g, 12p, 12u, and 12y) showed better antagonistic activities against FXR than compound 11. Remarkably, the most potent derivat...

Recently, new results on percolation of interdependent networks have shown that the percolation transition can be first order. In this paper we show that, when considering antagonistic interactions between interacting networks, the percolation process might present a bistability of the equilibrium solution. To this end, we introduce antagonistic interactions for which the functionality, or acti...

due to the high antagonistic activity of bacterium, bacillus subtilis (ehrenberg) cohn, three isolates (b.s.ham, 204 and 202) were selected and their efficacy were studied in control of sugar beetdamping–off caused by rhizoctonia solani , in  in vitro and in vivo conditions.  in dual culture on pda, all isolates of b.subtilis inhibited mycelial growth of r.solani.  significantly, volatile metab...

Peptide analogs of growth hormone-releasing hormone (GHRH) can potentially interact with vasoactive intestinal peptide (VIP) receptors (VPAC(1)-R and VPAC(2)-R) because of the structural similarities of these two hormones and their receptors. We synthesized four new analogs related to GHRH (JV-1-50, JV-1-51, JV-1-52, and JV-1-53) with decreased GHRH antagonistic activity and increased VIP antag...

Intorduction Dead Sea is a hypersaline lake with 34% salinity, gains its name due to the absence of any living macroscopic creatures. Despite the extreme hypersaline environment, it is a unique ecosystem for various halophilic microorganisms adapted to this environment. Aims & Objectives Halophilic microorganisms are known for various potential biotechnological applications, the purpose of th...

Very little is known about the interaction of bryophytes with bacteria. Therefore, we analyzed bacteria associated with three bryophyte species, Tortula ruralis, Aulacomnium palustre, and Sphagnum rubellum, which represent typical moss species of three nutrient-poor plant communities at the southern Baltic Sea coast in Germany. By use of two cultivation-independent techniques, denaturing gradie...

  Antibiotics are the best known products of actinomycete. Over 5,000 antibiotics have been identified from the cultures of Gram positive and Gram-negative organisms, and filamentous fungi, but only about 100 antibiotics have commercially been used to treat human, animal and plant diseases. The genus, Streptomycete, is responsible for the formation of more than 60% of known antibiotics. Bacteri...

the aim of the present study was to isolate cyanobacteria from oil refinery waste water and detection of antagonistic activity of their extracts on four species of pathogenic bacteria. the cyanobacterium was isolated and purified on blue green algae medium number 11 (bg-11) medium. methanol and water extracts prepared from the cultured cyanobacterium after 45 days growth on bg-11 medium. the bi...