PURPOSE To evaluate the efficacy of bromfenac ophthalmic solution 0.07% dosed once daily in achieving zero-to-trace (0-5 cells) anterior chamber cells, following cataract surgery with posterior chamber intraocular lens implantation. METHODS The study designed employed two Phase III, double-masked, placebo-controlled, multicenter clinical trials of 440 subjects, randomized to either bromfenac ...

A 54-year-old woman with an epiretinal membrane in her left eye accompanied by a shallow anterior chamber due to primary angle closure glaucoma underwent vitrectomy and cataract surgery. During the cataract surgery, immediately after the ultrasonic tip had been removed from the anterior chamber, anterior chamber flattening occurred. An intraoperative fundus examination showed the development of...

Background: It has been estimated that 67 million people worldwide are affected with a primary glaucoma and that one-third have primary angle closure glaucoma. We aimed to determine the biometric differences between the eyes of patients with acute attack of primary angle closure and their non-involved fellow eyes. Methods: Twenty eight patients with acute attack of primary angle closure were re...

PURPOSE To compare the measurement of anterior chamber depth exclusive of corneal thickness using Orbscan IIz and ultrasound biomicroscopy (UBM) and evaluate the repeatability of each method. METHODS Three consecutive measurements of anterior chamber depth were prospectively performed using Orbscan IIz and Paradigm 50-MHz UBM in 40 eyes in 20 individuals. Mean values were compared using the p...

PURPOSE Vitrectomy, when followed by cataract surgery, increases the risk of open-angle glaucoma. This study was conducted in patients to determine whether these procedures are associated with increased exposure of the trabecular meshwork to oxygen. METHODS Oxygen distribution was recorded with a fiberoptic probe in patients undergoing surgery for cataract, glaucoma, or retinal disease. pO(2)...

Perfusion studies of the anterior segment of the eye frequently involve an exchange of the contents of the anterior chamber. We here determined how much fluid was necessary to pass through the upstream tubing and anterior chamber such that the contents of the anterior chamber were adequately exchanged. We used fluorescein dextran (500 kD) to assess the adequacy of exchange of enucleated porcine...

background: it has been estimated that 67 million people worldwide are affected with a primary glaucoma and that one-third have primary angle closure glaucoma. we aimed to determine the biometric differences between the eyes of patients with acute attack of primary angle closure and their non-involved fellow eyes.   methods: twenty eight patients with acute attack of primary angle closure were ...

Ocular involvement with Gnathostoma spinigerum occurs years after the initial infection that is acquired by ingestion of poorly cooked, pickled seafood or water contaminated with third stage larvae. Here we report a case of gnathostomiasis of the left eye of a 32-year-old lady hailing from Meghalaya, India. Her vision had deteriorated to hand movement. Slit lamp examination revealed a live, act...

The anterior chambers of 27 rabbit eyes were perfused at constant pressure with room temperature (25 degrees C) or cooled (11 degrees C) balanced salt solution at constant flow rates of 4.8 ml/min or 8.5 ml/min. Intraocular temperature changes in the anterior chamber, anterior vitreous, mid vitreous, and posterior vitreous and on the retina surface were monitored with an intraocular thermocoupl...

The anterior chamber angle is the actual anatomical angle created by the root of the iris and the peripheral corneal vault. Within it lie the structures involved in the outflow passage of the aqueous, namely the trabecular meshwork and the Schlemm’s canal (figure 1). The depth of the angle in a healthy eye is approximately 30°, with the superior part usually less deep than the inferior half. Ho...