BACKGROUND Green tea polyphenol (GTP) suppresses malignancy in bladder cancer cell lines. However, the detail of its anti-carcinogenic effect in vivo is not fully understood. This study investigated the effect of GTP on bladder tumor size and angiogenesis in mice given N-butyl-(-4-hydroxybutyl) nitrosamine (BBN), with and without GTP. METHODS Eight-week-old female C3H/He mice were treated wit...

α-solanine, a steroidal glycoalkaloid in potato, was found to have proliferation-inhibiting and apoptosis-promoting effect on multiple cancer cells, such as clone, liver, melanoma cancer cells. However, the antitumor efficacy of α-solanine on pancreatic cancer has not been fully evaluated. In this study, we inquired into the anti-carcinogenic effect of α-solanine against human pancreatic cancer...

Colon cancer is one of the major causes of cancer-related death in the Western world. Although cytotoxic chemotherapeutic agents are available to treat the disease, these agents become ineffective as the disease advances to an invasive state. An alternative but viable approach to reduce the incidence of this deadly disease is then, to increase the dietary intake of relatively non-toxic fruits a...

In Hungary, focus of interest has been placed on methods by which the volume of the stem cells circulating within the body can be increased with the aim of regenerating the damaged tissues (i.e. brain, cardiovascular system) of the accrued stem cells. However, the means by which the stem cells are increased makes a difference. Some methods may even have a carcinogenic effect, while others may h...

During the course of a study of the effect of the oral administration of certain polycydic hydrocarbons on the growth of the rat,7 a paper by Haddow, Scott, and Scott2 appeared which reported that growth retardation had been produced in the rat by a single intraperitoneal injection of certain carcinogenic hydrocarbons. These authors further observed that similar injections of non-carcinogenic c...