Health technology The use of routine antenatal anti-D prophylaxis in the prevention of haemolytic disease in the newborn was examined. Two different target populations were considered, all pregnant women who were rhesus (RhD)-negative and women who were RhD-negative primigravidae only. The two different prophylactic treatments considered were Bio Products Laboratory (BPL) anti-D immunoglobulin(...

OBJECTIVE The purpose of this study was to compare the efficacy and side effects of intravenous immunoglobulin (IVIG) with intravenous anti-D immunoglobulin for treatment of newly diagnosed acute childhood Idiopathic thrombocytopenic purpura (ITP). METHODS Children (6 months to 14 years) with newly diagnosed acute ITP and platelet count below 20,000/ microL were randomized to receive single d...

Health technology The use of routine antenatal anti-D prophylaxis in the prevention of haemolytic disease in the newborn was examined. Two different target populations were considered, all pregnant women who were rhesus (RhD)-negative and women who were RhD-negative primigravidae only. The two different prophylactic treatments considered were Bio Products Laboratory (BPL) anti-D immunoglobulin(...

Bakcground: The aim of ITP treatment is to prevent intracranial hemorrhage and increase the platelet count rapidly. This study was conducted with the objective of comparing the efficacy of anti-D immunoglobulin (Ig) with dexamethasone in treating childhood ITP. Materials and Methods: In this randomized prospective control trial, 20 ITP patients (Platelet count<20,000/&micro;l) younger than...

Introduction While the use of elevated middle cerebral artery peak systolic velocity (MCA PSV) in assessing fetal anaemia is well known, its occurrence is uncommon due to the current practice of giving prophylactic doses of ultrafiltered Rh (D) immunoglobulin (anti-D) in Rh (D) negative women. In mothers who do not receive prophylaxis with Rh immunoglobulin, the overall risk of immunisation for...

objective anti-rh d igg is used for the prevention of anti-d antibody production in rh- individuals who have been exposed to rh+ red blood cells. the stability of igg preparations as a solution is low, with a shelf life of a year or more. formulation of anti-rh d igg as a lyophilized preparation would decrease its degradation rate and increases its shelf life. the objective of this study was to...