In this paper, a Reed-based composite (R) beads, combined with photocatalysis, for the oxidative degradation of fluoroquinolones ciprofloxacin (CIP) in simulated hospital wastewater was developed. It is well known that effluents present very diluted pollution (less than 5 mg/L), The first purpose, which concerns step to treat CIP solution (4 mg/L) via adsorption on beads continuous column syste...

DA Classen. Antibiotic bead pouch dressing. Can J Plast Surg 1996;4(4):199-202. The antibiotic bead pouch is a dressing consisting of antibiotic laden polymethylmethacrylate (PMMA) beads placed in a wound, which is covered by a porous membrane (Opsite). This paper outlines the method, rationale and results of the use of this dressing technique for extensive wounds before definitive wound closur...

Most epidural abscesses are a secondary lesion of pyogenic spondylodiscitis. An epidural abscess associated with pyogenic arthritis of the facet joint is quite rare. To the best of our knowledge, there is no report of the use of antibiotic-cement beads in the surgical treatment of an epidural abscess. This paper reports a 63-year-old male who sustained a 1-week history of radiating pain to both...

A polymeric-resin-based microbiological assay is shown to yield results consistent with classical inhibition zone theory. This novel assay is applicable to cycloheximide, an antifungal antibiotic, at concentrations below 1.0 mug/mL and up to 800 mug/mL. Addition of ethanol to the cut-out wells of the assay plate helps to release the antibiotic and drastically increases the inhibition zone size....

Objective: The aim of the study was to assess role antibiotic beads in management compound fracture long bone. Methods: Twenty-four patients with bone (Grade II, IIIA, and IIIB) operated initial debridement, stabilization, coated beads. All were followed-up till at least 6 months. evaluated clinically radiologically for functional outcome. Results: Seventeen (71%) male while 7 (29%) female. Mea...

OBJECTIVE To assess the use of antibiotic-loaded polymethyl methacrylate beads in the management of chronic osteomyelitis of different aetiologies: infected osteosynthesis, infected open fractures, and haematogenous osteomyelitis. METHODS Records of 49 patients with chronic osteomyelitis who were treated at Department of Orthopaedics, Kasturba Medical College, from 1995 to 1999 were studied r...

BACKGROUND AND PURPOSE Many investigations on biodegradable materials acting as an antibiotic carrier for local drug delivery are based on poly(lactide). However, the use of poly(lactide) implants in bone has been disputed because of poor bone regeneration at the site of implantation. Poly(trimethylene carbonate) (PTMC) is an enzymatically degradable polymer that does not produce acidic degrada...

OBJECTIVE To characterize the elution and bioactivity of metronidazole and gentamicin sulfate polymerized, individually and in combination, with polymethylmethacrylate (PMMA). STUDY DESIGN In vitro experimental study. METHODS PMMA beads containing metronidazole (3 concentrations), gentamicin sulfate, or metronidazole and gentamicin sulfate were immersed in 5 mL of phosphate-buffered saline ...

The use of antibiotic impregnated beads has been shown to be a valuable adjunct in the prevention of infection in open fractures. The bead pouch technique employs these beads within the wound, producing high local levels of antibiotic in a moist environment. This effectively inhibits bacterial colonisation and wound infection whilst preventing desiccation of structures such as bone and tendons....

An 8-year-old, male huacaya alpaca presented for a left mandibular swelling that was not responsive to antimicrobial treatment. A computed tomography scan obtained, confirming the presence of lytic bone destruction and primary osteomyelitis. Surgical debridement area performed surgical site packed with antibiotic-loaded calcium sulphate beads provide local antibiotic delivery support new format...