In vitro susceptibility testing of Fusarium is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are those of Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility (EUCAST), but breakpoints (BPs) h...

conclusions the monitoring of antifungal susceptibilities of candida species isolated from clinical sources is highly recommended for the efficient management of patients. moreover, the trailing effect should be taken into consideration once the interpretation of the results is intended. results among the tested antifungal drugs in this study, the highest rate of resistance was observed against...

background and purpose: candida species are the most common organisms involved in superficial fungal infections, worldwide. although econazole is among the most frequently used topical formulations for the treatment of candidiasis, no information is available regarding the susceptibility profiles of candida species in iran. materials and methods: in vitro susceptibility of 100 clinical candida ...

The availability of standardized antifungal susceptibility testing methodologies as well as the definition of interpretative breakpoints have made possible the establishment of useful correlations between in vitro testing data and clinical results with antifungal drugs such as fluconazole and itraconazole in patients with oropharyngeal candidiasis. The results obtained in these studies, however...

Introduction Compared to antibacterial drugs, antimicrobial agents available for treatment of invasive fungal infections are sparse. Amphotericin B (polyene) was the first drug introduced in the 1950s, followed by flucytosine (pyrimidine) in the 1970s, and first-generations azoles (fluconazole, itraconazole) in the 1990s. Triazoles (voriconazole, posaconalzole) and echinocandins (caspofungin, m...